Nicolas BLONDEAU – IPMC

Recherche

Intranet

Thème

Gérard LAMBEAU

Sophie BERAUD-DUFOUR

Biographie pas encore disponible.

Événements

Thèse d'Ilona LE GROUX

« Effets des Oméga-3 et de leurs dérivés oxygénés dans le diabète de type 2 » Directeurs de thèse : Dr. Nicolas […]

Actualités

Publication IPMC / Brain, Behavior, and Immunity / Équipe Barrès

La composition en acides gras de l’alimentation est à l’origine de la neuroinflammation et de l’altération du comportement dans l’obésité […]

Publication IPMC/J Cereb Blood Flow Metab./ Dr. Nicolas Blondeau/Equipe G. Lambeau

In close collaboration with the team of M. Tauc and D. Pisani (Université Côte d’Azur, CNRS, LP2M), our study identifies […]

Publications

Joseph S Tauskela, Nicolas Blondeau, How to Pick a Neuroprotective Drug in Stroke Without Losing Your Mind?, Life, 2025, 15 (6), pp.883. ⟨10.3390/life15060883⟩.

Didier F Pisani, Nicolas Blondeau, Deciphering the brain glucose metabolism: A gateway to innovative stroke therapies, Journal of Cerebral Blood Flow and Metabolism, In press, ⟨10.1177/0271678x251346277⟩.

Miled Bourourou, Nicolas Melis, Marc Cougnon, Gilbert Laffet, Christophe Duranton, Isabelle Rubera, Thomas Maurin, Catherine Heurteaux, Thierry Hauet, Maria Duca, Didier Pisani, Nicolas Blondeau, Michel Tauc, Targeting seryl-tRNA synthetase to unlock ischemic resilience in stroke – Insights from a proof-of-concept study, Journal of Cerebral Blood Flow and Metabolism, 2025, ⟨10.1177/0271678x251347810⟩.

I Legroux, S Beraud-Dufour, P Lebrun, L Balas, T Durand, Nicolas Blondeau, Alpha-Linolenic Acid: a pleiotropic option for protecting the brain from Ischemic stroke and managing metabolic comorbidities, The International Symposium on Neuroprotection and Neurorepair (ISN&N), Nov 2024, Potsdam, Germany.

Joseph S Tauskela, Amy Aylsworth, T. Comas, Umberto Banderali, Nicolas Blondeau, Marzia Martina, Optimization of Cell Penetrating Poly-Arginine Peptides to Provide a Superior Therapeutic Index Against Severe Excitotoxic Insults In Vitro, 11th International Symposium on Neuroprotection an Neurorepair 2024, Nov 2024, Potsdam, Germany.

Clara Sanchez, Cécilia Colson, Nadine Gautier, Pascal Noser, Juliette Salvi, Maxime Villet, Lucile Fleuriot, Caroline Peltier, Pascal Schlich, Frédéric Brau, Ariane Sharif, Ali Altintas, Ez-Zoubir Amri, Jean-Louis Nahon, Nicolas Blondeau, Alexandre Benani, Romain Barrès, Carole Rovère, Dietary fatty acid composition drives neuroinflammation and impaired behavior in obesity, Brain, Behavior, and Immunity, 2024, 117, pp.330-346. ⟨10.1016/j.bbi.2024.01.216⟩.

Veronika Brezani, Nicolas Blondeau, Jan Kotouček, Eva Klásková, Karel Šmejkal, Jan Hošek, Eliška Mašková, Pavel Kulich, Vilailak Prachyawarakorn, Catherine Heurteaux, Josef Mašek, Enhancing Solubility and Bioefficacy of Stilbenes by Liposomal Encapsulation─The Case of Macasiamenene F, ACS Omega, 2024, ⟨10.1021/acsomega.3c07380⟩.

Thierry Coppola, Guillaume Daziano, Ilona Legroux, Sophie Béraud-Dufour, Nicolas Blondeau, Patricia Lebrun, Unlocking Therapeutic Synergy: Tailoring Drugs for Comorbidities such as Depression and Diabetes through Identical Molecular Targets in Different Cell Types, Cells, 2023, 12 (23), pp.2768. ⟨10.3390/cells12232768⟩.

Laurence Balas, Sujit Kumar Dey, Sophie Béraud-Dufour, Dean Edward Riechers, Olivia Augusta Landau, Justine Bertrand-Michel, Thierry Durand, Nicolas Blondeau, Linotrins: Omega-3 oxylipins featuring an E,Z,E conjugated triene motif are present in the plant kingdom and alleviate inflammation in LPS-challenged microglial cells, European Journal of Medicinal Chemistry, 2022, 231, pp.114157. ⟨10.1016/j.ejmech.2022.114157⟩.

Michel Tauc, Marc Cougnon, Romain Carcy, Nicolas Melis, Thierry Hauet, Luc Pellerin, Nicolas Blondeau, Didier Pisani, The eukaryotic initiation factor 5A (eIF5A1), the molecule, mechanisms and recent insights into the pathophysiological roles, Cell & Bioscience, 2021, 11 (1), ⟨10.1186/s13578-021-00733-y⟩.

Romain Carcy, Marc Cougnon, Mallorie Poet, Manon Durandy, Antoine Sicard, Laurent Counillon, Nicolas Blondeau, Thierry Hauet, Michel Tauc, Didier Pisani, Targeting oxidative stress, a crucial challenge in renal transplantation outcome, Free Radical Biology and Medicine, 2021, 169, pp.258-270. ⟨10.1016/j.freeradbiomed.2021.04.023⟩.

Nicolas Blondeau, Combattre l’accident vasculaire cérébral en inhibant une enzyme liée à la voie de synthèse des polyamines, Médecine/Sciences, 2021, 37 (6-7), pp.575-577. ⟨10.1051/medsci/2021068⟩.

Marc Cougnon, Romain Carcy, Nicolas Melis, Isabelle Rubera, Christophe Duranton, Karine Dumas, Jean‐françois Tanti, Catherine Pons, Nicolas Soubeiran, Marina Shkreli, Thierry Hauet, Luc Pellerin, Sébastien Giraud, Nicolas Blondeau, Michel M. Tauc, Didier Pisani, Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney, Cell Death and Disease, 2021, 12 (4), ⟨10.1038/s41419-021-03577-z⟩.

Céline Cansell, Katharina Stobbe, Clara Sanchez, Ophélia Le Thuc, Coralie-Anne Mosser, Selma Ben-Fradj, Joris Leredde, Cynthia Lebeaupin, Delphine Debayle, Lucile Fleuriot, Frédéric Brau, Nadège Devaux, Alexandre Benani, Etienne Audinat, Nicolas Blondeau, Jean-Louis Nahon, Carole Rovère, Dietary fat exacerbates postprandial hypothalamic inflammation involving glial fibrillary acidic protein-positive cells and microglia in male mice, Glia, 2021, 69 (1), pp.42-60. ⟨10.1002/glia.23882⟩.

Guillaume Daziano, Nicolas Blondeau, Sophie Béraud-Dufour, Amar Abderrahmani, Carole Rovère, Catherine Heurteaux, Jean Mazella, Patricia Lebrun, Thierry Coppola, Sortilin-derived peptides promote pancreatic beta-cell survival through CREB signaling pathway, Pharmacological Research, 2021, 167, pp.105539. ⟨10.1016/j.phrs.2021.105539⟩.

Veronika Leláková, Sophie Béraud-Dufour, Jan Hošek, Karel Šmejkal, Vilailak Prachyawarakorn, Phanruethai Pailee, Catherine Widmann, Jiří Václavík, Thierry Coppola, Jean Mazella, Nicolas Blondeau, Catherine Heurteaux, Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia, Journal of Ethnopharmacology, 2020, pp.113147. ⟨10.1016/j.jep.2020.113147⟩.

Miled Bourourou, Elsa Gouix, Nicolas Melis, Jonas Friard, Catherine Heurteaux, Michel Tauc, Nicolas Blondeau, Inhibition of eIF5A hypusination pathway as a new pharmacological target for stroke therapy, Journal of Cerebral Blood Flow and Metabolism, 2020, pp.0271678X2092888. ⟨10.1177/0271678X20928882⟩.

Mathieu Carron, Fanny Hamard, Jacques Levraut, Nicolas Blondeau, An acute coronary syndrome in Antarctica, International maritime health, 2019, 70 (3), pp.167-170. ⟨10.5603/IMH.2019.0026⟩.

Thierry Coppola, Sophie Béraud-Dufour, Patricia Lebrun, Nicolas Blondeau, Bridging the Gap Between Diabetes and Stroke in Search of High Clinical Relevance Therapeutic Targets, NeuroMolecular Medicine, 2019, ⟨10.1007/s12017-019-08563-5⟩.

Michel Tauc, Nicolas Melis, Miled Bourourou, Sébastien Giraud, Thierry Hauet, Nicolas Blondeau, A new pharmacological preconditioning-based target: from drosophila to kidney transplantation, Conditioning Medicine, 2019.

Nicolas Blondeau, Sophie Béraud-Dufour, Patricia Lebrun, Céline Hivelin, Thierry Coppola, Sortilin in Glucose Homeostasis: From Accessory Protein to Key Player?, Frontiers in Pharmacology, 2019, 9, ⟨10.3389/fphar.2018.01561⟩.

Rossana Sirabella, Valeria Valsecchi, Serenella Anzilotti, Ornella Cuomo, Antonio Vinciguerra, Pasquale Cepparulo, Paola Brancaccio, Natascia Guida, Nicolas Blondeau, Lorella Canzoniero, Cristina Franco, Salvatore Amoroso, Lucio Annunziato, Giuseppe Pignataro, Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets, Frontiers in Neuroscience, 2018, 12, ⟨10.3389/fnins.2018.00510⟩.

Mathieu Carron, Nicolas Emeyriat, Jacques Levraut, Nicolas Blondeau, Cruise ship pathologies in remote regions, International maritime health, 2018, 69 (2), pp.75-83. ⟨10.5603/IMH.2018.0012⟩.

Tauskela Joseph S., Blondeau Nicolas, Requirement for preclinical prioritization of neuroprotective strategies in stroke: Incorporation of preconditioning, Conditioning Medicine, 2018.

Ophélia Le Thuc, Katharina Stobbe, Céline Cansell, Jean-Louis Nahon, Nicolas Blondeau, Carole Rovère, Hypothalamic Inflammation and Energy Balance Disruptions: Spotlight on Chemokines, Frontiers in Endocrinology, 2017, 8, ⟨10.3389/fendo.2017.00197⟩.

Joseph S Tauskela, Miled Bourourou, Nicolas Blondeau, Tackling issues in the path toward clinical translation in brain conditioning: Potential offered by nutraceuticals, Brain Circulation, 2017, ⟨10.4103/bc.bc_8_17⟩.

Nicolas Melis, Isabelle Rubera, Marc Cougnon, Sébastien Giraud, Baharia Mograbi, Amine Belaïd, Didier Pisani, Stephan Huber, Sandra Lacas-Gervais, Konstantina Fragaki, Nicolas Blondeau, Paul Vigne, Christian Frelin, Thierry Hauet, Christophe Duranton, Michel Tauc, Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome, Journal of the American Society of Nephrology, 2017, 28 (3), pp.811-822. ⟨10.1681/ASN.2016010012⟩.

Ophélia Le Thuc, Céline Cansell, Miled Bourourou, Raphaël Gp Denis, Katharina Stobbe, Nadège Devaux, Alice Guyon, Julie Cazareth, Catherine Heurteaux, William Rostène, Serge Luquet, Nicolas Blondeau, Jean‐louis Nahon, Carole Rovère, Central CCL2 signaling onto MCH neurons mediates metabolic and behavioral adaptation to inflammation, EMBO Reports, 2016, 17 (12), pp.1738-1752. ⟨10.15252/embr.201541499⟩.

Miled Bourourou, Catherine Heurteaux, Nicolas Blondeau, Alpha-linolenic acid given as enteral or parenteral nutritional intervention against sensorimotor and cognitive deficits in a mouse model of ischemic stroke, Neuropharmacology, 2016, 108, pp.60-72. ⟨10.1016/j.neuropharm.2016.04.040⟩.

Joseph Tauskela, Amy Aylsworth, Melissa Hewitt, Eric Brunette, Nicolas Blondeau, Failure and rescue of preconditioning-induced neuroprotection in severe stroke-like insults, Neuropharmacology, 2016, 105, pp.533-542. ⟨10.1016/j.neuropharm.2016.02.007⟩.

Nicolas Blondeau, Inger Lauritzen, Catherine Widmann, Michel Lazdunski, Catherine Heurteaux, A Potent Protective Role of Lysophospholipids Against Global Cerebral Ischemia and Glutamate Excitotoxicity in Neuronal Cultures, Journal of Cerebral Blood Flow and Metabolism, 2016, 22 (7), pp.821-834. ⟨10.1097/00004647-200207000-00007⟩.

Nicolas Blondeau, The nutraceutical potential of omega-3 alpha-linolenic acid in reducing the consequences of stroke, Biochimie, 2016, 120, pp.49-55. ⟨10.1016/j.biochi.2015.06.005⟩.

Ophélia Le Thuc, Nicolas Blondeau, Jean-Louis Nahon, Carole Rovère, The complex contribution of chemokines to neuroinflammation: switching from beneficial to detrimental effects, Annals of the New York Academy of Sciences, 2015, 1351 (1), pp.127-140. ⟨10.1111/nyas.12855⟩.

Nicolas Blondeau, Robert Lipsky, Miled Bourourou, Mark Duncan, Philip Gorelick, Ann Marini, Alpha-Linolenic Acid: An Omega-3 Fatty Acid with Neuroprotective Properties—Ready for Use in the Stroke Clinic?, BioMed Research International , 2015, 2015, pp.1-8. ⟨10.1155/2015/519830⟩.

E. Gouix, A. Buisson, A. Nieoullon, L. Kerkerian-Legoff, Js Tauskela, N. Blondeau, L. Had-Aissouni, Oxygen glucose deprivation-induced astrocyte dysfunction provokes neuronal death through oxidative stress, Pharmacological Research, 2014, 87, pp.8-17. ⟨10.1016/j.phrs.2014.06.002⟩.

Carine Nguemeni, Elsa Gouix, Miled Bourourou, Catherine Heurteaux, Nicolas Blondeau, Alpha-linolenic acid: A promising nutraceutical for the prevention of stroke, PharmaNutrition, 2013, 1 (1), pp.1-8.

Carine Nguemeni, Elsa Gouix, Miled Bourourou, Catherine Heurteaux, Nicolas Blondeau, Alpha-linolenic acid: A promising nutraceutical for the prevention of stroke, PharmaNutrition, 2013, 1 (1), pp.1-8. ⟨10.1016/j.phanu.2012.12.002⟩.

Dler Faieeq Darweesh Mahmood, Imene Jguirim-Souissi, El-Hadri Khadija, Nicolas Blondeau, Vimala Diderot, Souliman Amrani, Mohamed-Naceur Slimane, Tatiana Syrovets, Thomas Simmet, Mustapha Rouis, Peroxisome proliferator-activated receptor gamma induces apoptosis and inhibits autophagy of human monocyte-derived macrophages via induction of cathepsin L: potential role in atherosclerosis., Journal of Biological Chemistry, 2011, 286 (33), pp.28858-66. ⟨10.1074/jbc.M111.273292⟩.

Nicolas Blondeau, Alpha-linolenic omega-3 fatty acid for stroke protection: from brain preconditioning paradigm to nutrition, Oléagineux, Corps Gras, Lipides, 2011, ⟨10.1684/ocl.2011.0389⟩.

Grégory Conductier, Nicolas Blondeau, Alice Guyon, Jean-Louis Nahon, Carole Rovère, The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases., Journal of Neuroimmunology, 2010, 224 (1-2), pp.93-100. ⟨10.1016/j.jneuroim.2010.05.010⟩.

Nicholas Dodman, Nicolas Blondeau, Ann M Marini, Association of phenylbutazone usage with horses bought for slaughter: a public health risk., Food and Chemical Toxicology, 2010, 48 (5), pp.1270-4. ⟨10.1016/j.fct.2010.02.021⟩.

C. Nguemeni, B. Delplanque, C. Rovère, N. Simon-Rousseau, C. Gandin, G. Agnani, J. L. Nahon, C. Heurteaux, Nicolas Blondeau, Dietary supplementation of alpha-linolenic acid in an enriched rapeseed oil diet protects from stroke., Pharmacological Research, 2010, 61 (3), pp.226-33. ⟨10.1016/j.phrs.2009.12.007⟩.

Nicolas Blondeau, C. Nguemeni, David N Debruyne, Marie Piens, Xuan Wu, Hongna Pan, Xianzhang Hu, Carine Gandin, Robert H Lipsky, Jean-Christophe Plumier, Ann M Marini, Catherine Heurteaux, Subchronic Alpha-Linolenic Acid Treatment Enhances Brain Plasticity and Exerts an Antidepressant Effect: A Versatile Potential Therapy for Stroke., Neuropsychopharmacology, 2009, epub ahead of print. ⟨10.1038/npp.2009.84⟩.

Ann M Marini, Margherita Popolo, Hongna Pan, Nicolas Blondeau, Robert H Lipsky, Brain adaptation to stressful stimuli: a new perspective on potential therapeutic approaches based on BDNF and NMDA receptors., CNS Neurol Disord Drug Targets, 2008, 7 (4), pp.382-90.

A. Spahn, N. Blondeau, C. Heurteaux, F. Dehghani, A. Rami, Concomitant transitory up-regulation of X-linked inhibitor of apoptosis protein (XIAP) and the heterogeneous nuclear ribonucleoprotein C1-C2 in surviving cells during neuronal apoptosis., Neurochemical Research, 2008, 33 (9), pp.1859-68. ⟨10.1007/s11064-008-9658-0⟩.

Nicolas Blondeau, Yushuan Lai, Sarah Tyndall, Margherita Popolo, Kamil Topalkara, James Pru, Ling Zhang, Hyunghwan Kim, James Liao, Kan Ding, Christian Waeber, Distribution of sphingosine kinase activity and mRNA in rodent brain, Journal of Neurochemistry, 2007, 103 (2), pp.509-517. ⟨10.1111/j.1471-4159.2007.04755.x⟩.

Nicolas Blondeau, Olivier Pétrault, Stella Manta, Valérie Giordanengo, Pierre Gounon, Régis Bordet, Michel Lazdunski, Catherine Heurteaux, Polyunsaturated fatty acids are cerebral vasodilators via the TREK-1 potassium channel., Circulation Research, 2007, 101 (2), pp.176-84. ⟨10.1161/CIRCRESAHA.107.154443⟩.

Michel Mazzuca, Catherine Heurteaux, Abdelkrim Alloui, Sylvie Diochot, Anne Baron, Nicolas Voilley, Nicolas Blondeau, Pierre Escoubas, Agnès Gélot, Anny Cupo, Andreas Zimmer, Anne M Zimmer, Alain Eschalier, Michel Lazdunski, A tarantula peptide against pain via ASIC1a channels and opioid mechanisms., Nature Neuroscience, 2007, 10 (8), pp.943-945. ⟨10.1038/nn1940⟩.

A. Marini, X. Jiang, X. Wu, H. Pan, Z. Guo, M. Mattson, N. Blondeau, A. Novelli, H. Lipsky, Preconditioning and neurotrophins: a model for brain adaptation to seizures, ischemia and other stressful stimuli, Amino Acids, 2007, 32 (3), pp.299-304. ⟨10.1007/s00726-006-0414-y⟩.

Ambroise Garry, Bérengère Fromy, Nicolas Blondeau, Daniel Henrion, Frédéric Brau, Pierre Gounon, Nicolas Guy, Catherine Heurteaux, Michel Lazdunski, Jean Louis Saumet, Altered acetylcholine, bradykinin and cutaneous pressure-induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link., EMBO Reports, 2007, 8 (4), pp.354-9. ⟨10.1038/sj.embor.7400916⟩.

Alloui A, Zimmermann K, Mamet J, Duprat F, Noël J, Chemin J, Guy N, Blondeau N, Voilley N, Rubat-Coudert C, Borsotto M, Romey G, Heurteaux C, Reeh P, Eschalier A, Lazdunski M, TREK-1, a K+ channel involved in polymodal pain perception., EMBO J 2006 Jun; 25(11): 2368-76.

A. Alloui, K. Zimmermann, J. Mamet, Frederic Duprat, J. Noël, J. Chemin, N. Guy, N. Blondeau, N. Voilley, C. Rubat-Couderc, M. Borsotto, G. Romey, C. Heurteaux, P. Reeh, A. Eschalier, M. Lazdunski, TREK-1, a K+ channel involved in polymodal pain perception., EMBO Journal, 2006, 25, pp.2368-2376.

Nicolas Blondeau, Stéphane M. Schneider, Les acides gras essentiels de la famille des oméga-3 et la santé de la mère et de l’enfant Omega-3 fatty acids for mother and child health, Nutrition Clinique et Métabolisme, 2006, 20 (2), pp.68-72. ⟨10.1016/j.nupar.2006.04.008⟩.

C. Heurteaux, C. Laigle, N. Blondeau, G. Jarretou, M. Lazdunski, Alpha-Linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia, Neuroscience, 2006, 137, pp.241-251.

C. Heurteaux, G. Lucas, N. Guy, Malika El Yacoubi, S. Thümmler, X.D. Peng, F. Noble, N. Blondeau, C. Widmann, M. Borsotto, G. Gobbi, J.M. Vaugeois, G. Debonnel, M. Lazdunski, Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype, Nature Neuroscience, 2006, 9, pp.1134-1141. ⟨10.1038/nn1749⟩.

C. Heurteaux, N. Blondeau, Le role majeur du canal potassique TREK-1 dans la protection neuronale induite par les omega-3, OCL, 2005, xx, pp.77.

Blondeau N, Heurteaux C, [Cerebral tolerance: a promising choice towards new treatments for neurologic diseases]., Med Sci (Paris) 2004 Dec; 20(12): 1109-14.

C. Heurteaux, N. Guy, C. Laigle, N. Blondeau, Frederic Duprat, M. Mazzuca, L. Lang-Lazdunski, C. Widmann, M. Zanzouri, G. Romey, M. Lazdunski, TREK-1, a K+ channel involved in neuroprotection and general anesthesia, EMBO Journal, 2004, 23 (13), pp.2684-2695. ⟨10.1038/sj.emboj.7600234⟩.

C. Heurteaux, N. Guy, C. Laigle, N. Blondeau, M. Mazzuca, L. Lang-Lazdunski, C. Widmann, M. Zanzouri, G. Romey, M. Lazdunski, TREK-1, a K+ channel involved in neuroprotection and general anaesthesia, EMBO Journal, 2004, 23, pp.2684-2695.

C. Waeber, N. Blondeau, S. Salomone, Vascular sphingosine-1-phosphate S1P(1) and S1P(3) receptors, Drug News perspect., 2004, xx, pp.382.

N. Blondeau, C. Heurteaux, Cerebral Tolerance: a new challenge to identify targets for cerebral protection, Médecine/Sciences, 2004, 20, pp.1109-1114.

L. Lang-Lazdunski, N. Blondeau, G. Jarretou, M. Lazdunski, C. Heurteaux, Linolenic acid prevents neuronal cell death and paraplegia following transient spinal cord ischemia in rats, Journal of Vascular Surgery, 2003, 38, pp.564-575.

N. Blondeau, C. Widmann, M. Lazdunski, C. Heurteaux, Polyunsaturated fatty acids induce ischemic and epileptic tolerance, Neuroscience, 2002, 109, pp.231-241.

N. Blondeau, I. Lauritzen, C. Widmann, M. Lazdunski, C. Heurteaux, A potent protective role of lysophospholipids against global cerebral ischemia and glutamate-excitotoxicity in neuronal cultures, Journal of Cerebral Blood Flow and Metabolism, 2002, 22, pp.821-834.

N. Blondeau, C Widmann, M. Lazdunski, C. Heurteaux, POLYUNSATURATED FATTY ACIDS INDUCE ISCHEMIC AND EPILEPTIC TOLERANCE, Neuroscience, 2002, 109 (2), pp.231-241. ⟨10.1016/s0306-4522(01)00473-0⟩.

Nicolas Blondeau, Catherine Widmann, Michel Lazdunski, Catherine Heurteaux, Activation of the Nuclear Factor-κB Is a Key Event in Brain Tolerance, Journal of Neuroscience, 2001, 21 (13), pp.4668-4677. ⟨10.1523/JNEUROSCI.21-13-04668.2001⟩.

Mohamed Ettaiche, Catherine Heurteaux, Nicolas Blondeau, Marc Borsotto, Norbert Tinel, Michel Lazdunski, ATP-sensitive potassium channels (K ) in retina: a key role for ATP delayed ischemic tolerance, Brain Research, 2001, 890 (1), pp.118 - 129. ⟨10.1016/s0006-8993(00)03152-8⟩.

Inger Lauritzen, Nicolas Blondeau, Catherine Heurteaux, Catherine Widmann, Georges Romey, Michel Lazdunski, Polyunsaturated fatty acids are potent neuroprotectors, EMBO Journal, 2000, 19 (8), pp.1784-1793. ⟨10.1093/emboj/19.8.1784⟩.

N. Blondeau, H Plamondon, C Richelme, C. Heurteaux, M Lazdunski², K ATP CHANNEL OPENERS, ADENOSINE AGONISTS AND EPILEPTIC PRECONDITIONING ARE STRESS SIGNALS INDUCING HIPPOCAMPAL NEUROPROTECTION, Neuroscience, 2000, 100 (3), pp.465-474. ⟨10.1016/S0306-4522(00)00304-3⟩.

Hélène Plamondon, Nicolas Blondeau, Catherine Heurteaux, Michel Lazdunski, Mutually Protective Actions of Kainic Acid Epileptic Preconditioning and Sublethal Global Ischemia on Hippocampal Neuronal Death: Involvement of Adenosine A 1 Receptors and K ATP Channels, Journal of Cerebral Blood Flow and Metabolism, 1999, 19 (12), pp.1296-1308. ⟨10.1097/00004647-199912000-00002⟩.