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Publications
2024
Alpha-Linolenic Acid: a pleiotropic option for protecting the brain from Ischemic stroke and managing metabolic comorbidities,
The International Symposium on Neuroprotection and Neurorepair (ISN&N), Nov 2024, Potsdam, Germany.
2023
Unlocking Therapeutic Synergy: Tailoring Drugs for Comorbidities such as Depression and Diabetes through Identical Molecular Targets in Different Cell Types,
Cells, 2023, 12 (23), pp.2768. ⟨10.3390/cells12232768⟩.
2023
Identification of a key oncogenic role of p63 in altered-FGFR3 tumors through inference of bladder cancer gene regulatory network and functional validations,
2023.
2022
Integrated molecular and pharmacological characterization of patient-derived xenografts from bladder and ureteral cancers identifies new potential therapies,
Frontiers in Oncology, 2022, 12, ⟨10.3389/fonc.2022.930731⟩.
2022
Linotrins: Omega-3 oxylipins featuring an E,Z,E conjugated triene motif are present in the plant kingdom and alleviate inflammation in LPS-challenged microglial cells,
European Journal of Medicinal Chemistry, 2022, 231, pp.114157. ⟨10.1016/j.ejmech.2022.114157⟩.
2021
Sortilin-derived peptides promote pancreatic beta-cell survival through CREB signaling pathway,
Pharmacological Research, 2021, 167, pp.105539. ⟨10.1016/j.phrs.2021.105539⟩.
2020
Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia,
Journal of Ethnopharmacology, 2020, pp.113147. ⟨10.1016/j.jep.2020.113147⟩.
2019
Biatrial remodelling in atrial fibrillation: A three-dimensional and strain echocardiography insight,
Archives of cardiovascular diseases, 2019, 112, pp.585 - 593. ⟨10.1016/j.acvd.2019.06.010⟩.
2019
Bridging the Gap Between Diabetes and Stroke in Search of High Clinical Relevance Therapeutic Targets,
NeuroMolecular Medicine, 2019, ⟨10.1007/s12017-019-08563-5⟩.
2019
Sortilin in Glucose Homeostasis: From Accessory Protein to Key Player?,
Frontiers in Pharmacology, 2019, 9, ⟨10.3389/fphar.2018.01561⟩.
2019
Metabolic complications affecting adipose tissue, lipid and glucose metabolism associated with HIV antiretroviral treatment,
Expert Opinion on Drug Safety, 2019, 18 (9), pp.829-840. ⟨10.1080/14740338.2019.1644317⟩.
2019
Recurrent activating mutations of PPARγ associated with luminal bladder tumors,
Nature Communications, 2019, 10, pp.253. ⟨10.1038/s41467-018-08157-y⟩.
2018
An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers,
EMBO Molecular Medicine, 2018, 10 (4), pp.e8163. ⟨10.15252/emmm.201708163⟩.
2016
Potentiation of Calcium Influx and Insulin Secretion in Pancreatic Beta Cell by the Specific TREK-1 Blocker Spadin,
Journal of diabetes research, 2016, 2016, pp.Article ID 3142175. ⟨10.1155/2016/3142175⟩.
2016
Focal Adhesion Kinase-Dependent Role of the Soluble Form of Neurotensin Receptor-3/Sortilin in Colorectal Cancer Cell Dissociation,
International Journal of Molecular Sciences, 2016, 17 (11), pp.1860. ⟨10.3390/ijms17111860⟩.
2014
Impairement of HT29 Cancer Cells Cohesion by the Soluble Form of Neurotensin Receptor-3.,
Genes and Cancer, 2014, 5 (7-8), pp.240-249. ⟨10.18632/genesandcancer.22⟩.
2013
Focal adhesion kinase dependent activation of the PI3 kinase pathway by the functional soluble form of neurotensin receptor-3 in HT29 cells.,
International Journal of Biochemistry and Cell Biology, 2013, 45 (5), pp.952-9. ⟨10.1016/j.biocel.2013.01.020⟩.
2013
The Anti-Apoptotic Role of Neurotensin,
Cells, 2013, 2 (1), pp.124-135. ⟨10.3390/cells2010124⟩.
2012
Neurotensin and its receptors in the control of glucose homeostasis.,
Frontiers in Endocrinology, 2012, 3, pp.143. ⟨10.3389/fendo.2012.00143⟩.
2011
Neurotensin-induced Erk1/2 phosphorylation and growth of human colonic cancer cells are independent from growth factors receptors activation,
Biochemical and Biophysical Research Communications, 2011, 414 (1), pp.118-122. ⟨10.1016/j.bbrc.2011.09.034⟩.
2010
Neurotensin is a regulator of insulin secretion in pancreatic beta-cells.,
International Journal of Biochemistry and Cell Biology, 2010, 42 (10), pp.1681-8. ⟨10.1016/j.biocel.2010.06.018⟩.
2010
Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.,
PLoS Biol 2010 Apr; 8(4): e1000355.
2009
Neurotensin receptor-2 and -3 are crucial for the anti-apoptotic effect of neurotensin on pancreatic beta-TC3 cells.,
International Journal of Biochemistry and Cell Biology, 2009, 41 (12), pp.2398-402.
2009
Neurotensin receptor-2 and -3 are crucial for the anti-apoptotic effect of neurotensin on pancreatic β-TC3 cells,
International Journal of Biochemistry and Cell Biology, 2009, 41 (12), pp.2398-2402. ⟨10.1016/j.biocel.2009.04.002⟩.
2008
Neurotensin protects pancreatic beta cells from apoptosis.,
International Journal of Biochemistry and Cell Biology, 2008, 40 (10), pp.2296-302. ⟨10.1016/j.biocel.2008.03.015⟩.
2007
Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1.,
FEBS Journal, 2007, 274 (21), pp.5518-32. ⟨10.1111/j.1742-4658.2007.06068.x⟩.
2004
Conformational States of the Small G Protein Arf-1 in Complex with the Guanine Nucleotide Exchange Factor ARNO-Sec7,
Journal of Biological Chemistry, 2004, 279 (17), pp.17004-17012. ⟨10.1074/jbc.M312780200⟩.
2002
A journey through the exocytic pathway,
Journal of Cell Science, 2002, 115 (Pt 9), pp.1779-1780.
2001
Crystal structure of Sar1-GDP at 1.7 Å resolution and the role of the NH 2 terminus in ER export,
Journal of Cell Biology, 2001, 155 (6), pp.937-948. ⟨10.1083/jcb.200106039⟩.
2001
[28] Expression, purification, and measurements of activity of ARNO1, a guanine nucleotide exchange factor for ADP-ribosylation factor 1 (ARF1),
Methods Enzymol., 384 (6608), pp.264-271, 2001, ⟨10.1038/384481a0⟩.
1999
Dual Interaction of ADP Ribosylation Factor 1 with Sec7 Domain and with Lipid Membranes during Catalysis of Guanine Nucleotide Exchange,
Journal of Biological Chemistry, 1999, 274 (53), pp.37629-37636. ⟨10.1074/jbc.274.53.37629⟩.
1998
A glutamic finger in the guanine nucleotide exchange factor ARNO displaces Mg2+ and the beta -phosphate to destabilize GDP on ARF1,
EMBO Journal, 1998, 17 (13), pp.3651-3659. ⟨10.1093/emboj/17.13.3651⟩.
1998
Structure of the Sec7 domain of the Arf exchange factor ARNO,
Nature, 1998, 392 (6671), pp.101-105. ⟨10.1038/32210⟩.
1997
Role of Protein-Phospholipid Interactions in the Activation of ARF1 by the Guanine Nucleotide Exchange Factor Arno,
Journal of Biological Chemistry, 1997, 272 (35), pp.22221-22226. ⟨10.1074/jbc.272.35.22221⟩.
1997
N-Terminal Hydrophobic Residues of the G-Protein ADP-Ribosylation Factor-1 Insert into Membrane Phospholipids upon GDP to GTP Exchange †,
Biochemistry, 1997, 36 (15), pp.4675-4684. ⟨10.1021/bi962252b⟩.
1984
Beta-delayed neutron radioactivity of $^{15}$B,
Zeitschrift für Physik. A, Atoms and Nuclei, 1984, 319, pp.237-238.