Kevin LEBRIGAND – IPMC

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Nathalie LEROUDIER

About

Head of the Computational Biology & Omics Data Analysis (CoBiODA) Bioinformatics Hub at the Institute of Molecular and Cellular Pharmacology of the CNRS in Nice-Sophia-Antipolis. Expert in bioinformatics omics data analysis using R and Python statistical workflows. Since 2015, I focus my expertise on methodological developments for single cell and spatial transcriptomics, using 10x Genomics Chromium and Visium libraries sequenced on Oxford Nanopore Technology PromethION long-read sequencer to perform isoform-level profiling at single cell spatial resolution. Since 2022, my work is mainly dedicated to data analysis of highly multiplexed RNA in situ hybridization assays performed on Merscope (Vizgen) and Xenium (10xGenomics) commercial platforms using state-of-the-art python statistical workflows (Scanpy, Squidpy, SpatialData).

Events

Anna DIAMANT's thesis

«Computational methodology for analysis of cell type-specific RNA isoform expression with long-read sequencing». Thesis Directors: Georges VASSAUX & […]

News

IPMC / bioRxiv / CoBiODA bioinformatics hub

Imaging-based spatial isoform transcriptomics resolves transcript diversity at cellular and subcellular resolution https://www.biorxiv.org/content/10.64898/2026.09.22.753429v1 Spatial transcriptomics has transformed our understanding of […]

Projects

Omics Data Integration Network (ODIN)

The volume of data from biological experiments is constantly increasing. The storage, access and exploitation of this highly heterogeneous heterogeneous […]

Tools

Access bioinformatics tools developed by CoBiODA staff to support IPMC research teams https://github.com/cobioda

Publications

Dunot J, Gandin C, Truchi M, Pirro G, Moreno S, Launay A, Azoulay B, Landra H, Yishan SM, Buée L, Lebrigand K, Pousinha PA, Blum D, Mari B, Bethus I, Willem M, Marie H, AETA peptide contributes to Alzheimer's disease signature of synapse dysfunction., Acta Neuropathol 2026 Jun; 151(1): .

Mbouamboua Y, Lebrigand K, Nampoothiri S, Couralet M, Arguel MJ, Cotellessa L, Allet C, Prevot V, Barbry P, Giacobini P, A single-cell and spatial atlas of early human olfactory development., Nat Commun 2026 Apr; 17(1): .

Corinus A, Abélanet S, Dubreuil J, Zhu Z, Pisano S, Boscagli C, Gay AS, Debayle D, Truchi M, Lebrigand K, Lacas-Gervais S, Brau F, Descombes X, Rousselle P, Franco M, Luton F, Human mammary 3D spheroid models uncover the role of filopodia in breaching the basement membrane to facilitate invasion., Matrix Biol 2026 Feb; 143(): 36-47.

Truchi M, Gautier-Isola M, Savary G, Scribe C, Lingampally A, Cadis H, Baeri A, Magnone V, Girard-Riboulleau C, Arguel MJ, de Schutter C, Fassy J, Boukrout N, Larrue R, Martin N, Rezzonico R, Pluquet O, Perrais M, Hofman V, Marquette CH, Hofman P, Günther A, Ricard N, Barbry P, Leroy S, Lebrigand K, Bellusci S, Cauffiez C, Vassaux G, Pottier N, Mari B, Aging affects reprogramming of pulmonary capillary endothelial cells after lung injury in male mice., Nat Common 2025 Aug; 16(1): 7234.

Preda MB, Nastase-Rusu EG, Neculachi CA, Zhong X, Voellenkle C, Mazure NM, Balacescu O, Ivan C, Zheng, miR-210 locus deletion disrupts cellular homeostasis: an integrated genetic study., Sci Rep 2025 Jul; 15(1): 22659.

Berrebeh N, Mbouamboua Y, Thuillet R, Ottaviani M, Robert F, Kamel Chelgham M, Magnone V, Desroches-Castan A, Ricard N, Anegon I, Remy S, Schermuly RT, Lebrigand K, Kojonazarov B, Savale L, Humbert M, Bailly S, Barbry P, Tu L, Guignabert C, Bone morphogenetic protein-9 controls pulmonary vascular growth and remodeling., Proc Natl Acad Sci USA 2025 Jul; 122(26): e2410229122.

Fierville M, Lebrigand K, Barbry P, Descombes X, Linear structure unfolding: application to mouse brain in spatial transcriptomics., Annu Int Conf IEEE Eng Med Biol Soc 2025 Jul; 2025(): 1-6.

Copley RR, Buttin J, Arguel MJ, Williaume G, Lebrigand K, Barbry P, Hudson C, Yasuo H, Early transcriptional similarities between two distinct neural lineages during ascidian embryogenesis., Dev Biol 2024 Oct; 514(): 1-11.

Redman E, Fierville M, Cavard A, Plaisant M, Arguel MJ, Ruiz Garcia S, McAndrew EM, Girard-Riboulleau C, Lebrigand K, Magnone V, Ponzio G, Gras D, Chanez P, Abelanet S, Barbry P, Marcet B, Zaragosi LE, Cell Culture Differentiation and Proliferation Conditions Influence the In Vitro Regeneration of the Human Airway Epithelium., Am J Respir Cell Mol Biol 2024 Sep; 71(3): 267-281.

Kypraios A, Bennour J, Imbert V, David L, Calvo J, Pflumio F, Bonnet R, Couralet M, Magnone V, Lebrigand K, Barbry P, Rohrlich PS, Peyron JF, Identifying Candidate Gene Drivers Associated with Relapse in Pediatric T-Cell Acute Lymphoblastic Leukemia Using a Gene Co-Expression Network Approach., Cancers (Basel) 2024 Apr; 16(9): .

Zaragosi LE, Gouleau A, Delin M, Lebrigand K, Arguel MJ, Girard-Riboulleau C, Rios G, Redman E, Plaisant M, Waldmann R, Magnone V, Marcet B, Barbry P, Ponzio G, Combination of CRISPR-Cas9-RNP and Single-Cell RNAseq to Identify Cell State-Specific FOXJ1 Functions in the Human Airway Epithelium. Methods Mol Biol 2024; 2725(): 1-25.

Truchi M, Lacoux C, Gille C, Fassy J, Magnone V, Lopes Goncalves R, Girard-Riboulleau C, Manosalva-Pena I, Gautier-Isola M, Lebrigand K, Barbry P, Spicuglia S, Vassaux G, Rezzonico R, Barlaud M, Husband B, Detecting subtle transcriptomic perturbations induced by lncRNAs knock-down in single-cell CRISPRi screening using a new sparse supervised autoencoder neural network. Front Bioinform 2024; 4(): 1340339.

Vásquez-Pacheco E, Marega M, Lingampally A, Fassy J, Truchi M, Goth K, Trygub L, Taghizadeh S, Bartkuhn M, Alexopoulos I, Dong Y, Lebrigand K, Gunther A, Chen C, Zhang J, Chao CM, Al Alam D, El Agha E, Mari B, Bellusci S, Rivetti S, Highlighting fibroblast plasticity in lung fibrosis: the WI-38 cell line as a model for investigating the myofibroblast and lipofibroblast switch., Theranostics 2024; 14(9): 3603-3622.

Cavard A, Redman E, Mercey O, Abelanet S, Plaisant M, Arguel MJ, Magnone V, Ruiz García S, Rios G, Deprez M, Lebrigand K, Ponzio G, Caballero I, Barbry P, Zaragosi LE, Marcet B, The MIR34B/C genomic region contains multiple potential regulators of multiciliogenesis. FEBS Lett 2023 Jun; 597(12): 1623-1637.

Zapletalová M, Rancurel C, Industri B, Bardin M, Le Brigand K, Nicot P, Magnone V, Seassau A, Barbry P, Potěšil D, Zdráhal Z, Ponchet M, Lochman J, BABA-induced pathogen resistance: a multi-omics analysis of the tomato response reveals a hyper-receptive status involving ethylene., Hortic Res 2023 Jun; 10(6): uhad068.

Guilbaud E, Barouillet T, Ilie M, Borowczyk C, Ivanov S, Sarrazy V, Vaillant N, Ayrault M, Castiglione A, Rignol G, Brest P, Bazioti V, Zaitsev K, Lebrigand K, Dussaud S, Magnone V, Bertolotto C , Marchetti S, Irondelle M, Goldberg I, Huby T, Westerterp M, Gautier EL, Mari B, Barbry P, Hofman P, Yvan-Charvet L, Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion. Cell Stem Cell 2023 Jun; 30(6): 800-817.e9.

Lebrigand K, Bergenstråhle J, Thrane K, Mollbrink A, Meletis K, Barbry P, Waldmann R, Lundeberg J, The spatial landscape of gene expression isoforms in tissue sections., Nucleic Acids Res 2023 May; 51(8): e47.

Chu , Braun T, Mari B, Samakovlis C, Li X, Seeger W, Herold S, Zhang JS, Bellusci S, El Agha E, GLI1+ cells are a source of repair-supportive mesenchymal cells (RSMCs) during airway epithelial regeneration. Cell Mol Life Sci 2022 Nov; 79(11): 581.

Bian B, Paquet A, Arguel MJ, Meyer M, Peyre L, Chalabi A, Péré M, Lebrigand K, Waldmann R, Barbry P, Hofman P, Roux J, Coupling live-cell imaging and in situ isolation of the same single cell to profile the transient states of predicted drug-tolerant cells., STAR Protoc 2022 Sep; 3(3): 101600.

Feliz Morel ÁJ, Hasanovic A, Morin A, Prunier C, Magnone V, Lebrigand K, Aouad A, Cogoluegnes S, Favier J, Pasquier C, Mus-Veteau I, Persistent Properties of a Subpopulation of Cancer Cells Overexpressing the Hedgehog Receptor Patched., Pharmaceuticals 2022 May; 14(5): .

Rios G, Lacoux C, Leclercq V, Diamant A, Lebrigand K, Lazuka A, Soyeux E, Lacroix S, Fassy J, Couesnon A, Thiery R, Mari B, Pradier C, Waldmann R, Barbry P, Monitoring SARS-CoV-2 variant alterations in Nice neighborhoods by wastewater nanopore sequencing., Lancet Reg Health Eur 2021 Nov; 10(): 100202.

Arrighi N, Moratal C, Savary G, Fassy J, Nottet N, Pons N, Clément N, Fellah S, Larrue R, Magnone V, Lebrigand K, Pottier N, Dechesne C, Vassaux G, Dani C, Peraldi P, Mari B , The FibromiR miR-214-3p Is Upregulated in Duchenne Muscular Dystrophy and Promotes Differentiation of Human Fibro-Adipogenic Muscle Progenitors. Cells 2021 Jul; 10(7): .

Pandiani C, Strub T, Nottet N, Cheli Y, Gambi G, Bille K, Husser C, Dalmasso M, Béranger G, Lassalle S, Magnone V, Pédeutour F, Irondelle M, Maschi C, Nahon-Estève S, Martel A, Caujolle JP, Hofman P, LeBrigand K, Davidson I, Baillif S, Barbry P, Ballotti R, Bertolotto C, Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease. Cell Death Differ 2021 Jun; 28(6): 1990-2000.

Leon LM, Gautier M, Allan R, Ilié M, Nottet N, Pons N, Paquet A, Lebrigand K, Truchi M, Fassy J, Magnone V, Kinnebrew G, Radovich M, Cheok MH, Barbry P, Vassaux G, Marquette CH , Ponzio G, Ivan M, Pottier N, Hofman P, Mari B, Rezzonico R, Correction: The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress. Oncogene 2021 Apr; 40(14): 2621.

Caballero I, Ringot-Destrez B, Si-Tahar M, Barbry P, Guillon A, Lantier I, Berri M, Chevaleyre C, Fleurot I, Barc C, Ramphal R, Pons N, Paquet A, Lebrigand K, Baron C, Bähr A, Klymiuk N, Léonard R, Robbe-Masselot C, Evidence of early increased sialylation of airway mucins and defective mucociliary clearance in CFTR-deficient piglets., J Cyst Fibros 2021 Jan; 20(1): 173-182.

Moiseenko A, Vazquez-Armendariz AI, Kheirollahi V, Chu , Tata PR, Zhang JS, Bellusci S, El Agha E, Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration. Cell Rep 2020 Dec; 33(12): 108549.

Deprez M, Zaragosi LE, Truchi M, Becavin C, Ruiz García S, Arguel MJ, Plaisant M, Magnone V, Lebrigand K, Abelanet S, Brau F, Paquet A, Pe'er D, Marquette CH, Leroy S, Barbry P, A Single-Cell Atlas of the Human Healthy Airways., Am J Respir Crit Care Med 2020 Dec; 202(12): 1636-1645.

Ottaviani A, Eid R, Zoccola D, Pousse M, Dubal JM, Barajas E, Jamet K, Lebrigand K, Lapébie P, Baudoin C, Giraud-Panis MJ, Rouan A, Beauchef G, Guéré C, Vié K, Barbry P, Tambutté S, Gilson E, Allemand D, Longevity strategies in response to light in the reef coral Stylophora pistillata. Sci Rep 2020 Nov; 10(1): 19937.

Castagnola S, Cazareth J, Lebrigand K, Jarjat M, Magnone V, Delhaye S, Brau F, Bardoni B, Maurin T, Agonist-induced functional analysis and cell sorting associated with single-cell transcriptomics characterizes cell subtypes in normal and pathological brain., Genome Res 2020 Nov; 30(11): 1633-1642.

Meyer M, Paquet A, Arguel MJ, Peyre L, Gomes-Pereira LC, Lebrigand K, Mograbi B, Brest P, Waldmann R, Barbry P, Hofman P, Roux J, Profiling the Non-genetic Origins of Cancer Drug Resistance with a Single-Cell Functional Genomics Approach Using Predictive Cell Dynamics., Cell Syst 2020 Oct; 11(4): 367-374.e5.

Cambien B, Lebrigand K, Baeri A, Nottet N, Compin C, Lamit A, Ferraris O, Peyrefitte CN, Magnone V, Henriques J, Zaragosi LE, Giorgetti-Peraldi S, Bost F, Gautier-Isola M, Rezzonico R, Barbry P, Barthel R, Mari B, Vassaux G, Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics. PLoS Pathog 2020 Oct; 16(10): e1008660.

Baranek T, Lebrigand K, de Amat Herbozo C, Gonzalez L, Bogard G, Dietrich C, Magnone V, Boisseau C, Jouan Y, Trottein F, Si-Tahar M, Leite-de-Moraes M, Mallevaey T, Paget C, High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision., Cell Rep 2020 Sep; 32(10): 108116.

Lebrigand K, Magnone V, Barbry P, Waldmann R, High throughput error corrected Nanopore single cell transcriptome sequencing. Nat Commun 2020 Aug; 11(1): 4025.

Bassani I, Rancurel C, Pagnotta S, Orange F, Pons N, Lebrigand K, Panabières F, Counillon L, Noblin X, Galiana E, Transcriptomic and Ultrastructural Signatures of K+-Induced Aggregation in Phytophthora parasitica Zoospores., Microorganisms 2020 Jul; 8(7): .

Moreno Leon L, Gautier M, Allan R, Ilié M, Nottet N, Pons N, Paquet A, Lebrigand K, Truchi M, Fassy J, Magnone V, Kinnebrew G, Radovich M, Cheok MH, Barbry P, Vassaux G, Marquette CH, Ponzio G, Ivan M, Pottier N, Hofman P, Mari B, Rezzonico R, The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress. Oncogene 2019 Nov; 38(46): 7146-7165.

Ruiz García S, Deprez M, Lebrigand K, Cavard A, Paquet A, Arguel MJ, Magnone V, Truchi M, Caballero I, Leroy S, Marquette CH, Marcet B, Barbry P, Zaragosi LE, Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures. Development 2019 Oct; 146(20): .

Savary G, Dewaeles E, Diazzi S, Buscot M, Nottet N, Fassy J, Courcot E, Henaoui IS, Lemaire J, Martis N, Van der Hauwaert C, Pons N, Magnone V, Leroy S, Hofman V, Plantier L, Lebrigand K, Paquet A, Lino Cardenas CL, Vassaux G, Hofman P, Günther A, Crestani B, Wallaert B, Rezzonico R, Brousseau T, Glowacki F, Bellusci S, Perrais M, Broly F, Barbry P, Marquette CH, Cauffiez C, Mari B, Pottier N, The Long Noncoding RNA DNM3OS Is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-β and Pulmonary Fibrosis., Am J Respir Crit Care Med 2019 Jul; 200(2): 184-198.

Zarif H, Paquet A, Lebrigand K, Arguel MJ, Heurteaux C, Glaichenhaus N, Chabry J, Guyon A, Petit-Paitel A, CD4+ T Cells Affect the Thyroid Hormone Transport at the Choroid Plexus in Mice Raised in Enriched Environment., Neuroimmunomodulation 2019; 26(2): 59-66.

Medina C, da Rocha M, Magliano M, Raptopoulo A, Marteu N, Lebrigand K, Abad P, Favery B, Jaubert-Possamai S, Characterization of siRNAs clusters in Arabidopsis thaliana galls induced by the root-knot nematode Meloidogyne incognita., BMC Genomics 2018 Dec; 19(1): 943.

Giovannini-Chami L, Paquet A, Sanfiorenzo C, Pons N, Cazareth J, Magnone V, Lebrigand K, Chevalier B, Vallauri A, Julia V, Marquette CH, Marcet B, Leroy S, Barbry P, The «one airway, one disease» concept in light of Th2 inflammation., Eur Respir J 2018 Oct; 52(4): .

Maurin T, Lebrigand K, Castagnola S, Paquet A, Jarjat M, Popa A, Grossi M, Rage F, Bardoni B, HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile, Nucleic Acids Res 2018 Jul; 46(12): 6344-6355.

Peter J, De Chiara M, Friedrich A, Yue JX, Pflieger D, Bergström A, Sigwalt A, Barre B, Freel K, Llored A, Cruaud C, Labadie K, Aury JM, Istace B, Lebrigand K, Barbry P, Engelen S, Lemainque A, Wincker P, Liti G, Schacherer J, Genome evolution across 1,011 Saccharomyces cerevisiae isolates. Nature 2018 Apr; 556(7701): 339-344.

Zarif H, Nicolas S, Guyot M, Hosseiny S, Lazzari A, Canali MM, Cazareth J, Brau F, Golzné V, Dourneau E, Maillaut M, Luci C, Paquet A, Lebrigand K, Arguel MJ, Daoudlarian D, Heurteaux C, Glaichenhaus N, Chabry J, Guyon A, Petit-Paitel A, CD8+ T cells are essential for the effects of enriched environment on hippocampus-dependent behavior, hippocampal neurogenesis and synaptic plasticity., Brain Behav Immune 2018 Mar; 69(): 235-254.

Pruneau L, Lebrigand K, Mari B, Lefrançois T, Meyer DF, Vachiery N, Comparative Transcriptome Profiling of Virulent and Attenuated Ehrlichia ruminantium Strains Highlighted Strong Regulation of map1- and Metabolism Related Genes. Front Cell Infect Microbiol 2018; 8(): 153.

Zarif H, Hosseiny S, Paquet A, Lebrigand K, Arguel MJ, Cazareth J, Lazzari A, Heurteaux C, Glaichenhaus N, Chabry J, Guyon A, Petit-Paitel A, CD4+ T Cells Have a Permissive Effect on Enriched Environment-Induced Hippocampus Synaptic Plasticity., Front Synaptic Neurosci 2018; 10(): 14.

Medina C, da Rocha M, Magliano M, Ratpopoulo A, Revel B, Marteu N, Magnone V, Lebrigand K, Cabrera J, Barcala M, Silva AC, Millar A, Escobar C, Abad P, Favery B, Jaubert-Possamai S, Characterization of microRNAs from Arabidopsis galls highlights a role for miR159 in the plant response to the root-knot nematode Meloidogyne incognita., New Phytol 2017 Nov; 216(3): 882-896.

Lupu-Plesu M, Claren A, Martial S, N'Diaye PD, Lebrigand K, Pons N, Ambrosetti D, Peyrottes I, Feuillade J, Hérault J, Dufies M, Doyen J, Pagès G, Effects of proton versus photon irradiation on (lymph)angiogenic, inflammatory, proliferative and anti-tumor immune responses in head and neck squamous cell carcinoma., Oncogenesis 2017 Jul; 6(7): e354.

Arguel MJ, LeBrigand K, Paquet A, Ruiz García S, Zaragosi LE, Barbry P, Waldmann R, A cost effective 5΄ selective single cell transcriptome profiling approach with improved UMI design., Nucleic Acids Res 2017 Apr; 45(7): e48.

Mercey O, Popa A, Cavard A, Paquet A, Chevalier B, Pons N, Magnone V, Zangari J, Brest P, Zaragosi LE, Ponzio G, Lebrigand K, Barbry P, Marcet B, Characterizing isomiR variants within the microRNA-34/449 family. FEBS Lett 2017 Mar; 591(5): 693-705.

Beclin C, Follert P, Stappers E, Barral S, Coré N, Chevigny A, Magnone V, Lebrigand K, Bissels U, Huylebroeck D, Bosio A, Barbry P, Seuntjens E, Cremer H, Corrigendum: miR-200 family controls late steps of postnatal forebrain neurogenesis via Zeb2 inhibition., Sci Rep 2016 Dec; 6(): 39368.

Beclin C, Follert P, Stappers E, Barral S, Coré N, de Chevigny A, Magnone V, Lebrigand K, Bissels U, Huylebroeck D, Bosio A, Barbry P, Seuntjens E, Cremer H, miR-200 family controls late steps of postnatal brain neurogenesis via Zeb2 inhibition. SciRep 2016 Oct; 6(): 35729.

Lebrigand K, He LD, Thakur N, Arguel MJ, Polanowska J, Henrissat B, Record E, Magdelenat G, Barbe V, Raffaele S, Barbry P, Ewbank JJ, Comparative Genomic Analysis of Drechmeria coniospora Reveals Core and Specific Genetic Requirements for Fungal Endoparasitism of Nematodes., PLoS Genet 2016 May; 12(5): e1006017.

Garot A, Marquet M, Saintamand A, Bender S, Le Noir S, Rouaud P, Carrion C, Oruc Z, Bébin AG, Moreau J, Lebrigand K, Denizot Y, Alt FW, Cogné M, Pinaud E, Sequential activation and distinct functions for distal and proximal modules within the IgH 3′ regulatory region., Proc Natl Acad Sci USA 2016 Feb; 113(6): 1618-23.

Popa A, Lebrigand K, Barbry P, Waldmann R, Pateamine A-sensitive ribosome profiling reveals the scope of translation in mouse embryonic stem cells. BMC Genomics 2016 Jan; 17(): 52.

Popa A, Lebrigand K, Paquet A, Nottet N, Robbe-Sermesant K, Waldmann R, Barbry P, RiboProfiling: a Bioconductor package for standard Ribo-seq pipeline processing., F1000Res 2016 ; 5(): 1309.

Bertero T, Robbe-Sermesant K, Le Brigand K, Ponzio G, Pottier N, Rezzonico R, Mazure NM, Barbry P, Mari B, MicroRNA target identification: lessons from hypoxamiRs. Antioxid Redox Signal 2014 Sep; 21(8): 1249-68.

Gastaldi C, Bertero T, Xu N, Bourget-Ponzio I, Lebrigand K, Fourre S, Popa A, Cardot-Leccia N, Meneguzzi G, Sonkoly E, Pivarcsi A, Mari B, Barbry P, Ponzio G, Rezzonico R, miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma., Carcinogenesis 2014 May; 35(5): 1110-20.

Puissegur MP, Eichner R, Quelen C, Coyaud E, Mari B, Lebrigand K, Broccardo C, Nguyen-Khac F, Bousquet M, Brousset P, B-cell regulator of immunoglobulin heavy-chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells., Leukemia 2012 Oct; 26(10): 2224-32.

Giovannini-Chami L, Marcet B, Moreilhon C, Chevalier B, Illie MI, Lebrigand K, Robbe-Sermesant K, Bourrier T, Michiels JF, Mari B, Crénesse D, Hofman P, de Blic J, Castillo L, Albertini M, Barbry P, Distinct epithelial gene expression phenotypes in childhood respiratory allergy., Eur Respir J 2012 May; 39(5): 1197-205.

Bertero T, Grosso S, Robbe-Sermesant K, Lebrigand K, Hénaoui IS, Puisségur MP, Fourre S, Zaragosi LE, Mazure NM, Ponzio G, Cardinaud B, Barbry P, Rezzonico R, Mari B, «Seed-Milarity» confers to hsa-miR-210 and hsa-miR-147b similar functional activity., PLoS One 2012;7(9):e44919.

Lassalle S, Hofman V, Ilie M, Bonnetaud C, Puisségur MP, Brest P, Loubatier C, Guevara N, Bordone O, Cardinaud B, Lebrigand K, Rios G, Santini J, Franc B, Mari B, Al Ghuzlan A, Vielh P, Barbry P, Hofman P, Can the microRNA signature distinguish between thyroid tumors of uncertain malignant potential and other well-differentiated tumors of the thyroid gland?, Endocr Relat Cancer 2011 Oct; 18(5): 579-94.

Zaragosi LE, Wdziekonski B, Brigand KL, Villageois P, Mari B, Waldmann R, Dani C, Barbry P, Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis., Genome Biol 2011 Jul; 12(7): R64.

Simonet T, Zaragosi LE, Philippe C, Lebrigand K, Schouteden C, Augereau A, Bauwens S, Ye J, Santagostino M, Giulotto E, Magdinier F, Horard B, Barbry P, Waldmann R, Gilson E, The human TTAGGG repeat factors 1 and 2 bind to a subset of interstitial telomeric sequences and satellite repeats., Cell Res 2011 Jul; 21(7): 1028-38.

Puisségur MP, Mazure NM, Bertero T, Pradelli L, Grosso S, Robbe-Sermesant K, Maurin T, Lebrigand K, Cardinaud B, Hofman V, Fourre S, Magnone V, Ricci JE, Pouysségur J, Gounon P, Hofman P, Barbry P, Mari B, miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity., Cell Death Differ 2011 Mar; 18(3): 465-78.

Brest P, Lapaquette P, Souidi M, Lebrigand K, Cesaro A, Vouret-Craviari V, Mari B, Barbry P, Mosnier JF, Hébuterne X, Harel-Bellan A, Mograbi B, Darfeuille-Michaud A, Hofman P, A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease., Nat Genet 2011 Mar; 43(3): 242-5.

Leroy Q, Lebrigand K, Armougom F, Barbry P, Thiéry R, Raoult D, Coxiella burnetii transcriptional analysis reveals serendipity clusters of regulation in intracellular bacteria., PLoS One 2010 Dec; 5(12): e15321.

The Brigand K, Robbe-Sermesant K, Mari B, Barbry P, MiRonTop: mining microRNAs targets across large scale gene expression studies., Bioinformatics 2010 Dec; 26(24): 3131-2.

Cardinaud B, Moreilhon C, Marcet B, Robbe-Sermesant K, LeBrigand K, Mari B, Eclache V, Cymbalista F, Raynaud S, Barbry P, miR-34b/miR-34c: a regulator of TCL1 expression in 11q-chronic lymphocytic leukaemia?, Leukemia 2009 Nov; 23(11): 2174-7.

Pottier N, Maurin T, Chevalier B, Puisségur MP, Lebrigand K, Robbe-Sermesant K, Bertero T, Lino Cardenas CL, Courcot E, Rios G, Fourre S, Lo-Guidice JM, Marcet B, Cardinaud B, Barbry P, Mari B, Identification of keratinocyte growth factor as a target of microRNA-155 in lung fibroblasts: implication in epithelial-mesenchymal interactions., PLoS One 2009 Aug; 4(8): e6718.

Grosso S, Puissant A, Dufies M, Colosetti P, Jacquel A, Lebrigand K, Barbry P, Deckert M, Cassuto JP, Mari B, Auberger P, Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors., Mol Cancer Ther 2009 Jul; 8(7): 1924-33.

Horard B, Eymery A, Fourel G, Vassetzky N, Puechberty J, Roizes G, Lebrigand K, Barbry P, Laugraud A, Gautier C, Simon EB, Devaux F, Magdinier F, Vourc'h C, Gilson E, Global analysis of DNA methylation and transcription of human repetitive sequences., Epigenetics 2009 Jul; 4(5): 339-50.

Vautor E, Magnone V, Rios G, Le Brigand K, Bergonier D, Lina G, Meugnier H, Barbry P, Thiéry R, Pépin M, Genetic differences among Staphylococcus aureus isolates from dairy ruminant species: a single-dye DNA microarray approach., Vet Microbiol 2009 Jan; 133(1-2): 105-14.

Defamie V, Cursio R, Le Brigand K, Moreilhon C, Saint-Paul MC, Laurens M, Crenesse D, Cardinaud B, Auberger P, Gugenheim J, Barbry P, Mari B, Gene expression profiling of human liver transplants identifies an early transcriptional signature associated with initial poor graft function., Am J Transplant 2008 Jun; 8(6): 1221-36.

Hofman VJ, Moreilhon C, Brest PD, Lassalle S, Le Brigand K, Sicard D, Raymond J, Lamarque D, Hébuterne XA, Mari B, Barbry PJ, Hofman PM, Gene expression profiling in human gastric mucosa infected with Helicobacter pylori., Mod Pathol 2007 Sep; 20(9): 974-89.

Fitsialos G, Chassot AA, Turchi L, Dayem MA, LeBrigand K, Moreilhon C, Meneguzzi G, Buscà R, Mari B, Barbry P, Ponzio G, Transcriptional signature of epidermal keratinocytes subjected to in vitro scratch wounding reveals selective roles for ERK1/2, p38, and phosphatidylinositol 3-kinase signaling pathways., J Biol Chem 2007 May; 282(20): 15090-102.

Brigand K, Barbry P, Mediante: a web-based microarray data manager., Bioinformatics 2007 May; 23(10): 1304-6.

Triboulet R, Mari B, Lin YL, Chable-Bessia C, Bennasser Y, Lebrigand K, Cardinaud B, Maurin T, Barbry P, Baillat V, Reynes J, Corbeau P, Jeang KT, Benkirane M, Suppression of microRNA-silencing pathway by HIV-1 during virus replication., Science 2007 Mar; 315(5818): 1579-82.

Le Brigand K, Russell R, Moreilhon C, Rouillard JM, Jost B, Amiot F, Magnone V, Bole-Feysot C, Rostagno P, Virolle V, Defamie V, Dessen P, Williams G, Lyons P, Rios G, Mari B, Gulari E, Kastner P, Gidrol X, Freeman TC, Barbry P, An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes., Nucleic Acids Res 2006 Jul; 34(12): e87.