Projets, outils et publications – IPMC

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Projects

Impact of lipid nature on neuroinflammation and glial reactivity, associated with the development of obesity.

Overview Keywords: Lipids, Neuroinflammation, Glial reactivity, Nutritional obesity This project aims to understand the mechanisms involved in the response […]

EXPOSURE: EXPOsome Signatures of Ultra-processed food pollutants: outcomes on brain Regulation

Key words: Pollutants, Phthalates, Plastics, Ultra-processed food, Exposome, Brain disorders. DESCRIPTION OF THE PROJECT EXPOSURE: EXPOsome Signatures of Ultra-processed food pollutants: outcomes on […]

Neuroinflammation and dysregulation of eating behavior

The projects developed in this second research axis are at the interface between neuroimmunoendocrinology, nutrition and metabolism. […]

Reprogramming of lipid homeostatic pathways by ZIKV proteins

Many viruses exploit host cell membranes and lipid metabolism to ensure their replication. The Zika virus, in particular, hijacks membranes […]

Role of VAPA-mediated membrane contact sites in lung surfactant production

This project aims to understand how membrane contact sites contribute to the production of pulmonary surfactant, a lipid-rich substance essential […]

Brain-heart coupling in emotional regulation

Emotions have a profound impact on heart function, mediated by complex interactions between the brain and autonomic nervous system. Emotional […]

Improved fertility

Food intake and epigenetic modifications of spermatozoa

The epithelium of the respiratory tract: a protective ecosystem

The airway epithelium lines the nose, trachea, and bronchi. It is made up of different types of cells […]

Microbiota, immunity, and neurodevelopment

Deciphering the molecular mechanisms of phosphatidylinositol distribution

Phosphatidylinositol (PI) is a unique lipid because it is the precursor to phosphoinositides, such as PI4P and PI(4,5)P2, which […]

Physiological and pathophysiological implication of the TRAAK channel.

Description: The laboratory is interested in potassium channels of the two-pore channel family, and more recently in […]

Tools

A bioinformatic tool allowing the easy retrieval of promoter of genes and the search of transcription factors consensus motifs.

Viewer of the Department of Cellular and Molecular Biology at the University of Arizona

Interactive Fluorescence Dye and Filter Database by Carl Zeiss

Fluorescence Spectra Viewer from BdBiosciences

To guide your choices of fluorochromes, web tools for interactive visualization of spectra

Access bioinformatics tools developed by CoBiODA staff to support IPMC research teams https://github.com/cobioda

ABBA and BraiAn

ABBA is a set of software component which allows to register images of thin serial biological tissue sections, cut in […]

A bioinformatics tool for determining the presence of lipid arrangement defects in models of biological membranes obtained […]

The following link provides access to HeliQuest, a bioinformatics tool allowing the analysis of amphipathic helices and searching for sequences presenting […]

Publications

Filippo La Greca, Elisa Zianni, Ilaria Cerchiaro, Michela Gusmini, Giulia Coccia, Alexandre Carrea, Silvia Pelucchi, Carlo Castoldi, Davide Maggioni, Elena Marcello, Bianca Ambrogina Silva, Fabrizio Gardoni, Monica DiLuca & Diego Scheggia, Individual differences in prosocial learning are represented in the hippocampal dorsal CA1, Nat Neurosci (2026). https://doi.org/10.1038/s41593-026-02292-2.

Sandrine Cestèle, Alexander J. Harper, Sebastian Marra, Nathalie Leroudier, Raffaella Rusconi, Sandra Dhifallah, Iain A Horrocks, Fenella J. Kirkham, Iona MR Morgan, Jaspal Singh, Daniel J. Stobo, Joseph D Symonds, Sameer M Zuberi, Massimo Mantegazza, Andreas Brunklaus, Elicited Repetitive Daily Blindness Associated With Gain-of-Function SCN1A Variants and Responsiveness to Sodium Channel Blockers, Neurol. Broom. 2026 Apr 22;12(3):e200352.

Fanny Eysert, Gaëlle Deportes, Elodie Delaquaize, Mounia Chami, Peripheral alterations of mitochondrial function and mitophagy in Alzheimer's disease: from fundamental research to clinical perspectives, Curr Opin Neurol. 2026 Apr 1;39(2):185-191. .

Athénaïs Genin, Alicia Janvier, Tristan Moujellil-Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto, Long-lasting astrocyte remodeling in Dravet Syndrome Scn1a+/– mouse model, Epilepsia 2026 Mar 17.

S. Dean, N. Georgiou, R. Poirier, WR Doar, D. Brill, Denovan Chauveau, C. Cerrone, J. Austermann, , Last interglacial relative sea-level changes at Myrtle Beach, South Carolina, Quaternary Science Reviews, 2026, 375, 109769 (18p.). ⟨10.1016/j.quascirev.2025.109769⟩.

Gabriel Rovere, Beatriz CD Cuyabano, Florence Phocas, Modeling breeding programs considering social behavior in large groups of farmed fish, 2026.

Aram Hayrapetyan, Vladimir Makarenko, Armen Tumasyan, Wolfgang Adam, Janik Walter Andrejkovic, Lisa Benato, Thomas Bergauer, Marko Dragicevic, Cristina Giordano, Priya Sajid Hussain, Manfred Jeitler, Natascha Krammer, Ang Li, Dietrich Liko, Mark Matthewman, Ivan Mikulec, Jochen Schieck, Robert Schöfbeck, Dennis Schwarz, Maryam Shooshtari, Mangesh Sonawane, Wolfgang Waltenberger, Claudia-Elisabeth Wulz, Tahys Janssen, Hyejin Kwon, Daniel Ocampo Henao, Thomas van Laer, Pierre van Mechelen, Jas Bi…, Simultaneous probe of the charm and bottom quark Yukawa couplings using ttH events, Phys.Rev.Lett., 2026, 136 (1), pp.011801. ⟨10.1103/9nwb-splk⟩.

Ramos Dos Santos L, Duplan E, Debord J, Fremont G, Minniti J, Lauritzen I, Mutez E, Leghay C, Chartier-Harlin MC, Checler F, Alves da Costa C, PRKN/parkin-mediated control of SNCA (synuclein alpha) and chaperone-mediated autophagy are defective in cellular, mice models and Parkinson disease-affected brains., Autophagy 2026 May; (): .

Abélanet S, Pagnotta S, Brau F, Péquignot M, Scheuermann V, Lacas-Gervais S, Rovere C, Corinus A, Della-Croce L, Delettre C, Luton F, Franco M, EFA6A regulates retinal function through the control of photoreceptor cell activity and structure., iScience 2026 Apr; 29(4): 115179.

Hertereau L, Barthe M, Lamghari N, Merida P, Pommier G, Pinel E, Swain J, Muriaux D, Osman-Ponchet H, Braud VM, Human keratinocytes exhibit limited potential for SARS-CoV-2 infection despite ACE2 and mature cathepsin L expression., JID Innov 2026 Mar; 6(2): 100447.