Pathophysiology of Neural Circuits and Behavior
Members
About
Our team is interested in the modulation of neuronal plasticity in physiological and pathological conditions. Solid expertise within the team in electrophysiology in vitro (field and patch clamp on slice) and in behavior allows us a transversal approach from molecular mechanisms to behavioral output. To manipulate the cellular mechanisms involved in various pathologies, we use a viral approach for protein expression in vivo as well as transgenic mouse lines. Currently, we are also developing biochemical and cellular imaging tools to complete our transversal approach. We also collaborate with national and international teams for biochemical and neurocomputational analyzes of neuronal function.
Marie-Barik Team Christmas Secret Santa Diner 2024
«The «scent»-sational role of GnRH neurons»
«The Gut-Brain Axix and the Control of Appetite»
«AETA, a new neuromodulator of the NMDA receptor in the hippocampus and its role in Alzheimer’s disease« Thesis Director: Hélène […]
«Cortico-Striatal Dynamics in Memory Automation» Thesis Director: Prof. Ingrid Bethus, Institute of Molecular and Cellular Pharmacology, […]
«APOE Isoforms: Tau Polymorphism and Bioactivity»
«Mesopontine cholinergic modulation of adaptive behaviors: vulnerability to environmental stressors» Thesis Director: Mr. Jacques BARIK & Mr. Sebastian […]
«Role of the sodium leak channel NALCN in midbrain dopamine neurons»
«How can functional vision be restored in a visual system deprived of photoreceptors?«
Events
«The «scent»-sational role of GnRH neurons»
«The Gut-Brain Axix and the Control of Appetite»
«AETA, a new neuromodulator of the NMDA receptor in the hippocampus and its role in Alzheimer’s disease« Thesis Director: Hélène […]
«Cortico-Striatal Dynamics in Memory Automation» Thesis Director: Prof. Ingrid Bethus, Institute of Molecular and Cellular Pharmacology, […]
«APOE Isoforms: Tau Polymorphism and Bioactivity»
«Mesopontine cholinergic modulation of adaptive behaviors: vulnerability to environmental stressors» Thesis Director: Mr. Jacques BARIK & Mr. Sebastian […]
«Role of the sodium leak channel NALCN in midbrain dopamine neurons»
«How can functional vision be restored in a visual system deprived of photoreceptors?«
News
An APP fragment controls both ionotropic and non-ionotropic NMDA receptor signaling Link to article Neuron Article […]
Université Côte d'Azur has selected four teacher-researchers to join the Collegium of Advanced Studies, launched by IdEx in 2024. In […]
«AETA, a novel neuromodulator of the NMDA receptor in the hippocampus and its role in Alzheimer’s disease»: PhD supervisor […]
«"A common thread between stress and anxiety: the VTA-amygdala pathway" Link to the article: https://www.biologicalpsychiatryjournal.com/article/S0006-3223(25)01121-7/fulltext
Nicotine: More than just an addictive molecule? A new study reveals that nicotine – the psychoactive substance in […]
A conference-debate entitled «Not Even Scared!» at the Café du Cycliste in Nice. Link to the article: “Not Even […]
Projects
Depression and anxiety disorders are common mental illnesses and are often associated with addictions (e.g., tobacco, alcohol […]
Amyloid precursor protein (APP) is a key protein involved in the etiology of AD. This protein is cleaved into several […]
Emotions have a profound impact on heart function, mediated by complex interactions between the brain and autonomic nervous system. Emotional […]