Miguel SALINAS

2022

Verkest C, Salinas M, Diochot S, Deval E, Lingueglia E, Baron A, Mechanisms of Action of the Peptide Toxins Targeting Human and Rodent Acid-Sensing Ion Channels and Relevance to Their In Vivo Analgesic Effects., Toxins (Basel) 2022 Oct; 14(10): .

2021

Salinas M, Kessler P, Douguet D, Sarraf D, Tonali N, Thai R, Servent D, Lingueglia E, Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat acid-sensing ion channel 1a., Neuropharmacology 2021 Mar; 185(): 108453.

2017

Besson T, Lingueglia E, Salinas M, Pharmacological modulation of Acid-Sensing Ion Channels 1a and 3 by amiloride and 2-guanidine-4-methylquinazoline (GMQ)., Neuropharmacology 2017 Oct; 125(): 429-440.

2016

Besson T, Debayle D, Diochot S, Salinas M, Lingueglia E, Low cost venom extractor based on Arduino(®) board for electrical venom extraction from arthropods and other small animals., Toxicon 2016 Aug; 118(): 156-61.

2016

Mourier G, Salinas M, Kessler P, Stura EA, Leblanc M, Tepshi L, Besson T, Diochot S, Baron A, Douguet D, Lingueglia E, Servent D, Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition., J Biol Chem 2016 Feb; 291(6): 2616-29.

2014

Salinas M, Besson T, Delettre Q, Diochot S, Boulakirba S, Douguet D, Lingueglia E, Binding site and inhibitory mechanism of the mambalgin-2 pain-relieving peptide on acid-sensing ion channel 1a., J Biol Chem 2014 May; 289(19): 13363-73.

2013

Baron A, Diochot S, Salinas M, Deval E, Noël J, Lingueglia E, Venom toxins in the exploration of molecular, physiological and pathophysiological functions of acid-sensing ion channels., Toxicon 2013 Dec; 75(): 187-204.

2012

Diochot S, Baron A, Salinas M, Douguet D, Scarzello S, Dabert-Gay AS, Debayle D, Friend V, Alloui A, Lazdunski M, Lingueglia E, Black mamba venom peptides target acid-sensing ion channels to abolish pain., Nature 2012 Oct; 490(7421): 552-5.

2012

Delaunay A, Gasull X, Salinas M, Noël J, Friend V, Lingueglia E, Deval E, Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions., Proc Natl Acad Sci U S A 2012 Aug; 109(32): 13124-9.

2010

Deval E, Gasull X, Noël J, Salinas M, Baron A, Diochot S, Lingueglia E, Acid-sensing ion channels (ASICs): pharmacology and implication in pain., Pharmacol Ther 2010 Dec; 128(3): 549-58.

2010

Noël J, Salinas M, Baron A, Diochot S, Deval E, Lingueglia E, Current perspectives on acid-sensing ion channels: new advances and therapeutic implications., Expert Rev Clin Pharmacol 2010 May; 3(3): 331-46.

2009

Salinas M, Lazdunski M, Lingueglia E, Structural elements for the generation of sustained currents by the acid pain sensor ASIC3., J Biol Chem 2009 Nov; 284(46): 31851-9.

2007

Diochot S, Salinas M, Baron A, Escoubas P, Lazdunski M, Peptides inhibitors of acid-sensing ion channels., Toxicon 2007 Feb; 49(2): 271-84.

2006

Deval E, Friend V, Thirant C, Salinas M, Jodar M, Lazdunski M, Lingueglia E, Regulation of sensory neuron-specific acid-sensing ion channel 3 by the adaptor protein Na+/H+ exchanger regulatory factor-1., J Biol Chem 2006 Jan; 281(3): 1796-807.

2006

Salinas M, Rash LD, Baron A, Lambeau G, Escoubas P, Lazdunski M, The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a., J Physiol 2006 Jan; 570(Pt 2): 339-54.

2004

Deval E, Salinas M, Baron A, Lingueglia E, Lazdunski M, ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1., J Biol Chem 2004 May; 279(19): 19531-9.

2004

Diochot S, Baron A, Rash LD, Deval E, Escoubas P, Scarzello S, Salinas M, Lazdunski M, A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons., EMBO J 2004 Apr; 23(7): 1516-25.

2002

Baron A, Deval E, Salinas M, Lingueglia E, Voilley N, Lazdunski M, Protein kinase C stimulates the acid-sensing ion channel ASIC2a via the PDZ domain-containing protein PICK1., J Biol Chem 2002 Dec; 277(52): 50463-8.

2002

Nicod M, Michlig S, Flahaut M, Salinas M, Fowler Jaeger N, Horisberger JD, Rossier BC, Firsov D, A novel vasopressin-induced transcript promotes MAP kinase activation and ENaC downregulation., EMBO J 2002 Oct; 21(19): 5109-17.

2001

Robert-Nicoud M, Flahaut M, Elalouf JM, Nicod M, Salinas M, Bens M, Doucet A, Wincker P, Artiguenave F, Horisberger JD, Vandewalle A, Rossier BC, Firsov D, Transcriptome of a mouse kidney cortical collecting duct cell line: effects of aldosterone and vasopressin., Proc Natl Acad Sci U S A 2001 Feb; 98(5): 2712-6.

1999

Salinas M, Reyes R, Lesage F, Fosset M, Heurteaux C, Romey G, Lazdunski M, Cloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structure., J Biol Chem 1999 Apr; 274(17): 11751-60.

1998

Reyes R, Duprat F, Lesage F, Fink M, Salinas M, Farman N, Lazdunski M, Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney., J Biol Chem 1998 Nov; 273(47): 30863-9.

1997

Salinas M, Duprat F, Heurteaux C, Hugnot JP, Lazdunski M, New modulatory alpha subunits for mammalian Shab K+ channels., J Biol Chem 1997 Sep; 272(39): 24371-9.

1997

Salinas M, de Weille J, Guillemare E, Lazdunski M, Hugnot JP, Modes of regulation of shab K+ channel activity by the Kv8.1 subunit., J Biol Chem 1997 Mar; 272(13): 8774-80.

1996

Hugnot JP, Salinas M, Lesage F, Guillemare E, de Weille J, Heurteaux C, Mattéi MG, Lazdunski M, Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels., EMBO J 1996 Jul; 15(13): 3322-31.