5th International ACC Symposium: An Outlook to Current and Future Research on the Biology of Adrenocortical Carcinoma: Diagnostic and Therapeutic Applications. – IPMC

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Intranet

Thème

The lipidome associated with the γ-secretase complex is required for its integrity and activity.

Pateamine A-sensitive ribosome profiling reveals the scope of translation in mouse embryonic stem cells.

Présentation

Groundbreaking progress has been recently made in elucidating the signaling pathways that are altered in adrenocortical carcinoma (ACC), an endocrine malignancy that still has an unfavorable prognosis, and in understanding its genomic structure. These advances need now to be translated to create cellular and animal models more relevant to human disease in order to develop new and more effective diagnostic procedures and targeted therapies against this deadly malignancy.