Thierry COPPOLA – IPMC

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Actualités

Inserm : les chercheurs de l'IPMC accueillent les malades

Le 14 juin 2025, l’IPMC a accueilli plusieurs associations de patients pour une matinée d’échanges autour de la douleur, de […]

Publications

Chato-Astrain I, Pronot M, Coppola T, Martin S, Molecular Organization and Regulation of the Mammalian Synapse by the Post-Translational Modification SUMOylation., Cells 2024 Feb; 13(5): .

Coppola T, Daziano G, Legroux I, Béraud-Dufour S, Blondeau N, Lebrun P, Unlocking Therapeutic Synergy: Tailoring Drugs for Comorbidities such as Depression and Diabetes through Identical Molecular Targets in Different Cell Types., Cells 2023 Dec; 12(23): .

Coppola T, Beraud-Dufour S, Lebrun P, Blondeau N, Bridging the Gap Between Diabetes and Stroke in Search of High Clinical Relevance Therapeutic Targets., Neuromolecular Med 2019 Dec; 21(4): 432-444.

Béraud-Dufour S, Devader C, Massa F, Roulot M, Coppola T, Mazella J, Focal Adhesion Kinase-Dependent Role of the Soluble Form of Neurotensin Receptor-3/Sortilin in Colorectal Cancer Cell Dissociation., Int J Mol Sci 2016 Nov; 17(11): .

Massa F, Devader C, Lacas-Gervais S, Béraud-Dufour S, Coppola T, Mazella J, Impairement of HT29 Cancer Cells Cohesion by the Soluble Form of Neurotensin Receptor-3., Genes Cancer 2014 Jul; 5(7-8): 240-249.

Moha Ou Maati H, Veyssiere J, Labbal F, Coppola T, Gandin C, Widmann C, Mazella J, Heurteaux C, Borsotto M, Spadin as a new antidepressant: absence of TREK-1-related side effects., Neuropharmacology 2012 Jan; 62(1): 278-88.

Massa F, Tormo A, Béraud-Dufour S, Coppola T, Mazella J, Neurotensin-induced Erk1/2 phosphorylation and growth of human colonic cancer cells are independent from growth factors receptors activation., Biochem Biophys Res Commun 2011 Oct; 414(1): 118-22.

Mazella J, Pétrault O, Lucas G, Deval E, Béraud-Dufour S, Gandin C, El-Yacoubi M, Widmann C, Guyon A, Chevet E, Taouji S, Conductier G, Corinus A, Coppola T, Gobbi G, Nahon JL, Heurteaux C, Borsotto M, Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design., PLoS Biol 2010 Apr; 8(4): e1000355.

Coppola T, Béraud-Dufour S, Antoine A, Vincent JP, Mazella J, Neurotensin protects pancreatic beta cells from apoptosis., Int J Biochem Cell Biol 2008 ; 40(10): 2296-302.

Cheviet S, Coppola T, Regazzi R, Functional assays for the investigation of the role of Rab GTPase effectors in dense core granule release., Methods Enzymol 2005 ; 403(): 57-71.

Abderrahmani A, Niederhauser G, Plaisance V, Roehrich ME, Lenain V, Coppola T, Regazzi R, Waeber G, Complexin I regulates glucose-induced secretion in pancreatic beta-cells., J Cell Sci 2004 May; 117(Pt 11): 2239-47.

Coppola T, Perret-Menoud V, Gattesco S, Magnin S, Pombo I, Blank U, Regazzi R, The death domain of Rab3 guanine nucleotide exchange protein in GDP/GTP exchange activity in living cells., Biochem J 2002 Mar; 362(Pt 2): 273-9.

Coppola T, Magnin-Luthi S, Perret-Menoud V, Gattesco S, Schiavo G, Regazzi R, Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin., J Biol Chem 2001 Aug; 276(35): 32756-62.

Coppola T, Perret-Menoud V, Lüthi S, Farnsworth CC, Glomset JA, Regazzi R, Disruption of Rab3-calmodulin interaction, but not other effector interactions, prevents Rab3 inhibition of exocytosis., EMBO J 1999 Nov; 18(21): 5885-91.

Joberty G, Stabila PF, Coppola T, Macara IG, Regazzi R, High affinity Rab3 binding is dispensable for Rabphilin-dependent potentiation of stimulated secretion., J Cell Sci 1999 Oct; 112 ( Pt 20)(): 3579-87.

Mazella J, Botto JM, Guillemare E, Coppola T, Sarret P, Vincent JP, Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain., J Neurosci 1996 Sep; 16(18): 5613-20.

Lesage F, Duprat F, Fink M, Guillemare E, Coppola T, Lazdunski M, Hugnot JP, Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain., FEBS Lett 1994 Oct; 353(1): 37-42.

Coppola T, Waldmann R, Borsotto M, Heurteaux C, Romey G, Mattéi MG, Lazdunski M, Molecular cloning of a murine N-type calcium channel alpha 1 subunit. Evidence for isoforms, brain distribution, and chromosomal localization., FEBS Lett 1994 Jan; 338(1): 1-5.

Auguste P, Hugues M, Borsotto M, Thibault J, Romey G, Coppola T, Lazdunski M, Characterization and partial purification from pheochromocytoma cells of an endogenous equivalent of scyllatoxin, a scorpion toxin which blocks small conductance Ca(2+)-activated K+ channels., Brain Res 1992 Dec; 599(2): 230-6.

Miraglia del Giudice M, Decimo F, Miraglia del Giudice M, Coppola T, [Possible factors of early sensitization in infant allergic asthma]., Arch Monaldi Mal Torace 1989 ; 44(4-6): 615-24.

Barhanin J, Coppola T, Schmid A, Borsotto M, Lazdunski M, The calcium channel antagonists receptor from rabbit skeletal muscle. Reconstitution after purification and subunit characterization., Eur J Biochem 1987 May; 164(3): 525-31.

Schmid A, Barhanin J, Mourre C, Coppola T, Borsotto M, Lazdunski M, Antibodies reveal the cytolocalization and subunit structure of the 1,4-dihydropyridine component of the neuronal Ca2+ channel., Biochem Biophys Res Commun 1986 Sep; 139(3): 996-1002.

Miraglia del Giudice M, Capristo AF, Mirra G, Maiello N, Coppola T, [Controlled double-blind study on the efficacy of clofedanol-sobrerol in the treatment of pediatric pertussis]., Minerva Pediatr 1984 Dec; 36(23-24): 1199-206.