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Présentation

Responsable valorisation IPMC

Experte senior en transfert de technologies à la Direction Scientifique de CNRS Innovation

Déléguée Scientifique auprès de la Direction Générale Déléguée à l’Innovation du CNRS

Publications

2019
Arhatte M, Gunaratne GS, El Boustany C, Kuo IY, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-Gervais S, Ehrlich BE, Marchant JS, Savage AM, van Eeden FJM, Wilkinson RN, Demolombe S, Honoré E, Patel A, TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells., Nat Commun 2019 May; 10(1): 2024.
2016
Martins JR, Penton D, Peyronnet R, Arhatte M, Moro C, Picard N, Kurt B, Patel A, Honoré E, Demolombe S, Piezo1-dependent regulation of urinary osmolarity., Pflugers Arch 2016 Jul; 468(7): 1197-1206.
2016
Retailleau K, Arhatte M, Demolombe S, Jodar M, Baudrie V, Offermanns S, Feng Y, Patel A, Honoré E, Duprat F, Smooth muscle filamin A is a major determinant of conduit artery structure and function at the adult stage., Pflugers Arch 2016 Jul; 468(7): 1151-1160.
2016
Retailleau K, Arhatte M, Demolombe S, Peyronnet R, Baudrie V, Jodar M, Bourreau J, Henrion D, Offermanns S, Nakamura F, Feng Y, Patel A, Duprat F, Honoré E, Arterial Myogenic Activation through Smooth Muscle Filamin A., Cell Rep 2016 Mar; 14(9): 2050-2058.
2015
Retailleau K, Duprat F, Arhatte M, Ranade SS, Peyronnet R, Martins JR, Jodar M, Moro C, Offermanns S, Feng Y, Demolombe S, Patel A, Honoré E, Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling., Cell Rep 2015 Nov; 13(6): 1161-1171.
2015
Patel A, Demolombe S, Honoré E, An alternative to force., Elife 2015 Jun; 4(): .
2015
Honoré E, Martins JR, Penton D, Patel A, Demolombe S, The Piezo Mechanosensitive Ion Channels: May the Force Be with You!, Rev Physiol Biochem Pharmacol 2015 ; 169(): 25-41.
2014
Sivagangabalan G, Nazzari H, Bignolais O, Maguy A, Naud P, Farid T, Massé S, Gaborit N, Varro A, Nair K, Backx P, Vigmond E, Nattel S, Demolombe S, Nanthakumar K, Regional ion channel gene expression heterogeneity and ventricular fibrillation dynamics in human hearts., PLoS One 2014 ; 9(1): e82179.
2013
Peyronnet R, Martins JR, Duprat F, Demolombe S, Arhatte M, Jodar M, Tauc M, Duranton C, Paulais M, Teulon J, Honoré E, Patel A, Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells., EMBO Rep 2013 Dec; 14(12): 1143-8.
2013
Demolombe S, Duprat F, Honoré E, Patel A, Slower Piezo1 inactivation in dehydrated hereditary stomatocytosis (xerocytosis)., Biophys J 2013 Aug; 105(4): 833-4.
2012
Jeyaraj D, Haldar SM, Wan X, McCauley MD, Ripperger JA, Hu K, Lu Y, Eapen BL, Sharma N, Ficker E, Cutler MJ, Gulick J, Sanbe A, Robbins J, Demolombe S, Kondratov RV, Shea SA, Albrecht U, Wehrens XH, Rosenbaum DS, Jain MK, Circadian rhythms govern cardiac repolarization and arrhythmogenesis., Nature 2012 Feb; 483(7387): 96-9.
2010
Jonsson MK, Vos MA, Duker G, Demolombe S, van Veen TA, Gender disparity in cardiac electrophysiology: implications for cardiac safety pharmacology., Pharmacol Ther 2010 Jul; 127(1): 9-18.
2010
Leoni AL, Gavillet B, Rougier JS, Marionneau C, Probst V, Le Scouarnec S, Schott JJ, Demolombe S, Bruneval P, Huang CL, Colledge WH, Grace AA, Le Marec H, Wilde AA, Mohler PJ, Escande D, Abriel H, Charpentier F, Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model., PLoS One 2010 Feb; 5(2): e9298.
2009
Alders M, Koopmann TT, Christiaans I, Postema PG, Beekman L, Tanck MW, Zeppenfeld K, Loh P, Koch KT, Demolombe S, Mannens MM, Bezzina CR, Wilde AA, Haplotype-sharing analysis implicates chromosome 7q36 harboring DPP6 in familial idiopathic ventricular fibrillation., Am J Hum Genet 2009 Apr; 84(4): 468-76.
2009
Gaborit N, Wichter T, Varro A, Szuts V, Lamirault G, Eckardt L, Paul M, Breithardt G, Schulze-Bahr E, Escande D, Nattel S, Demolombe S, Transcriptional profiling of ion channel genes in Brugada syndrome and other right ventricular arrhythmogenic diseases., Eur Heart J 2009 Feb; 30(4): 487-96.
2008
Cardin S, Pelletier P, Libby E, Le Bouter S, Xiao L, Kääb S, Demolombe S, Glass L, Nattel S, Marked differences between atrial and ventricular gene-expression remodeling in dogs with experimental heart failure., J Mol Cell Cardiol 2008 Dec; 45(6): 821-31.
2007
Gaborit N, Le Bouter S, Szuts V, Varro A, Escande D, Nattel S, Demolombe S, Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart., J Physiol 2007 Jul; 582(Pt 2): 675-93.
2006
Lamirault G, Gaborit N, Le Meur N, Chevalier C, Lande G, Demolombe S, Escande D, Nattel S, Léger JJ, Steenman M, Gene expression profile associated with chronic atrial fibrillation and underlying valvular heart disease in man., J Mol Cell Cardiol 2006 Jan; 40(1): 173-84.
2005
Guo W, Jung WE, Marionneau C, Aimond F, Xu H, Yamada KA, Schwarz TL, Demolombe S, Nerbonne JM, Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction., Circ Res 2005 Dec; 97(12): 1342-50.
2005
Gaborit N, Steenman M, Lamirault G, Le Meur N, Le Bouter S, Lande G, Léger J, Charpentier F, Christ T, Dobrev D, Escande D, Nattel S, Demolombe S, Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation., Circulation 2005 Jul; 112(4): 471-81.
2005
Ouvrard-Pascaud A, Sainte-Marie Y, Bénitah JP, Perrier R, Soukaseum C, Nguyen Dinh Cat A, Royer A, Le Quang K, Charpentier F, Demolombe S, Mechta-Grigoriou F, Beggah AT, Maison-Blanche P, Oblin ME, Delcayre C, Fishman GI, Farman N, Escoubet B, Jaisser F, Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias., Circulation 2005 Jun; 111(23): 3025-33.
2001
Demolombe S, Lande G, Charpentier F, van Roon MA, van den Hoff MJ, Toumaniantz G, Baro I, Guihard G, Le Berre N, Corbier A, de Bakker J, Opthof T, Wilde A, Moorman AF, Escande D, Transgenic mice overexpressing human KvLQT1 dominant-negative isoform. Part I: Phenotypic characterisation., Cardiovasc Res 2001 May; 50(2): 314-27.
1999
Mohammad-Panah R, Demolombe S, Neyroud N, Guicheney P, Kyndt F, van den Hoff M, Baró I, Escande D, Mutations in a dominant-negative isoform correlate with phenotype in inherited cardiac arrhythmias., Am J Hum Genet 1999 Apr; 64(4): 1015-23.
1998
Hollande E, Fanjul M, Chemin-Thomas C, Devaux C, Demolombe S, Van Rietschoten J, Guy-Crotte O, Figarella C, Targeting of CFTR protein is linked to the polarization of human pancreatic duct cells in culture., Eur J Cell Biol 1998 Jul; 76(3): 220-7.
1998
Pollard H, Remy JS, Loussouarn G, Demolombe S, Behr JP, Escande D, Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells., J Biol Chem 1998 Mar; 273(13): 7507-11.
1998
Mohammad-Panah R, Demolombe S, Riochet D, Leblais V, Loussouarn G, Pollard H, Baró I, Escande D, Hyperexpression of recombinant CFTR in heterologous cells alters its physiological properties., Am J Physiol 1998 Feb; 274(2): C310-8.
1996
Demolombe S, Baró I, Bebok Z, Clancy JP, Sorscher EJ, Thomas-Soumarmon A, Pavirani A, Escande D, A method for the rapid detection of recombinant CFTR during gene therapy in cystic fibrosis., Gene Ther 1996 Aug; 3(8): 685-94.
1996
Henry P, Demolombe S, Pucéat M, Escande D, Adenosine A1 stimulation activates delta-protein kinase C in rat ventricular myocytes., Circ Res 1996 Jan; 78(1): 161-5.
1991
Tigaud JD, Demolombe S, Bastion Y, Bryon PA, Coiffier B, Ifosfamide continuous infusion plus etoposide in the treatment of elderly patients with aggressive lymphoma: a phase II study., Hematol Oncol 1991 ; 9(4-5): 225-33.