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A search for the standard model (SM) Higgs boson (H) produced with transverse momentum (pT) greater than 450 GeV and decaying to a charm quark-antiquark (cc¯) pair is presented. The search is performed using proton-proton collision data collected at s=13 TeV by the CMS experiment at the LHC, corresponding to an integrated luminosity of 138 fb-1. Boosted H→cc¯ decay products are reconstructed as a single large-radius jet and identified using a deep neural network charm tagging technique. The method is validated by measuring the Z→cc¯ decay process, which is observed in association with jets at high pT for the first time with a signal strength of 1.00-0.14+0.17(syst)±0.08(theo)±0.06(stat), defined as the ratio of the observed process rate to the SM expectation. The observed (expected) upper limit on σ(H)B(H→cc¯) is set at 47 (39) times the SM prediction at 95% confidence level.