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The extracellular regulated kinase-1 (ERK1) controls regulated alpha-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein.
ADAM10 pharmacological inhibition modifies the expression of components of the dopaminergic system
PublicationMuscarinic receptors M1 and M3 induce the physiological metabolism of PrPc and βAPP by modulating the phosphorylation and activity of ADAM 17
Team: Pathophysiology of Alzheimer's and Parkinson's Diseases
Bruno VINCENT
