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IPMC / bioRxiv / CoBiODA bioinformatics hub

Imaging-based spatial isoform transcriptomics resolves transcript diversity at cellular and subcellular resolution https://www.biorxiv.org/content/10.64898/2026.09.22.753429v1 Spatial transcriptomics has transformed our understanding of […]

THE CONVERSATION: Parkinson's: Advances in understanding a key molecule of the disease

Link to the article: https://theconversation.com/parkinson-avancees-dans-la-comprehension-dune-molecule-cle-de-la-maladie-282783 We know that Parkinson's disease, which affects more than 10 million people in […]

Success Teams: Scientists Take the Plunge 🏊‍♂️👩‍🍳

82 students from the "Objectives: Guidance & Success" program, from four schools in the region (Valbonne International High School, middle schools […]

Publication IPMC/Systems Biology and Applications- Nature/ Dr Jérémie ROUX

The effectiveness of a drug depends on the molecular state of each cell. Within a clonal population, the same drug acts on […]

Events

Thesis by Rafael LOPES GONCALVES (Thesis director: Dr. Georges VASSAUX / Dr. Roger REZZONICO)

«Study of the response of pulmonary epithelial cells to various cancer-related stresses: toxicological aspects and functional study […]

Thesis by Benjamin AZOULAY (Thesis Director: Dr. Hélène MARIE / Dr. Ingrid BETHUS)

«Involvement of the APP-derived peptide AETA in the oscillatory dynamics of the Hippocampo-Prefrontal networks»

Thesis by Aurélie WUERTZER-LEPLUS (Thesis Director: Dr. Massimo MANTEGAZZA / Pr. Denys FONTAINE)

«Treatment of refractory pain by deep brain stimulation of the anterior cingulum: a study of clinical effects and mechanisms […]

Thesis by Tyffany MIGEVENT (Thesis director: Dr. Massimo MANTEGAZZA / Fabrice DUPRAT)

«Impact of repeated epileptic seizures on the mechanisms of sudden unexpected death in epilepsy (SUDEP) in […]

Latest publications

Sowmya Narayan, Christina Beer, Veronika Kovarova, Carlo Castoldi, Tibor Stark, Beatrice Dal Bianco, Simone Röh, Susann Sauer, Joeri Bordes, Stoyo Karamihalev, Shiladitya Mitra, Patricia Maidana Miguel, Bonnie Alberry, Darina Czamara, Patricia P. Silveira, Michael Czisch, Bianca Silva, Elisabeth B. Binder, and Mathias V. Schmidt, Multilevel sex-influenced neurobiological signatures of early life adversity, PNAS, 2026. https://www.pnas.org/doi/10.1073/pnas.2603982123.

Joana Gomes-Ribeiro, Jacques Barik, Sebastian Fernandez, Ventral tegmental area circuits in defensive states: Emerging mechanisms of fear and anxiety, Trends Neurosci. 2026 Jul 7:S0166-2236(26)00124-4. doi: 10.1016/j.tins.2026.06.008..

Filippo La Greca, Elisa Zianni, Ilaria Cerchiaro, Michela Gusmini, Giulia Coccia, Alexandre Carrea, Silvia Pelucchi, Carlo Castoldi, Davide Maggioni, Elena Marcello, Bianca Ambrogina Silva, Fabrizio Gardoni, Monica DiLuca & Diego Scheggia, Individual differences in prosocial learning are represented in the dorsal hippocampal CA1, Nat Neurosci (2026). https://doi.org/10.1038/s41593-026-02292-2.

Sandrine Cestèle, Alexander J. Harper, Sebastian Marra, Nathalie Leroudier, Raffaella Rusconi, Sandra Dhifallah, Iain A Horrocks, Fenella J. Kirkham, Iona MR Morgan, Jaspal Singh, Daniel J. Stobo, Joseph D Symonds, Sameer M Zuberi, Massimo Mantegazza, Andreas Brunklaus, Elicited Repetitive Daily Blindness Associated With Gain-of-Function SCN1A Variants and Responsiveness to Sodium Channel Blockers, Neurol. Broom. 2026 Apr 22;12(3):e200352.

Fanny Eysert, Gaëlle Deportes, Elodie Delaquaize, Mounia Chami, Peripheral alterations of mitochondrial function and mitophagy in Alzheimer's disease: from fundamental research to clinical perspectives, Curr Opin Neurol. 2026 Apr 1;39(2):185-191. .

Athénaïs Genin, Alicia Janvier, Tristan Moujellil-Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto, Long-lasting astrocyte remodeling in Dravet Syndrome Scn1a+/– mouse model, Epilepsia 2026 Mar 17.