Molecular Properties	Mammalian 2P channels		Functional properties

Structure and assembly of 2P domain K+ channels

Last update: 9 / 2 / 2001

Table of contents

• Secondary structure
• Putative assembly

Secondary structure

These channels are characterised by 4 transmembrane segments (S1 to S4) and 2 P domains (P1 and P2). They also display a long extracellular loop. The NH2 and COOH terminus are intracellular.

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Putative assembly

According to the structure of these channels, we expect the assembly of 2 subunits to form a functional channel.

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Molecular Properties	Mammalian 2P channels		Functional properties