ER export: public transportation by the COPII coach.

Intranet

Theme

A TREK-1-like potassium channel in atrial cells inhibited by beta-adrenergic stimulation and activated by volatile anesthetics.

SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis.

About

The COPII coat produces ER-derived transport vesicles. Recent findings suggest that the COPII coat is a highly dynamic polymer and that efficient capture of cargo molecules into COPII vesicles depends on several parameters, including export signals, membrane environment, metabolic control and the presence of a repertoire of COPII subunit homologs.